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Abstract
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of type 2 diabetes. Several targets to account for its therapeutic effects have been proposed, but a recent paper suggests a novel mechanism in which it antagonizes the cyclic AMP-dependent effects of glucagon on hepatic glucose production.
Original language | English |
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Pages (from-to) | 313-4 |
Number of pages | 2 |
Journal | Cell Metabolism |
Volume | 17 |
Issue number | 3 |
DOIs | |
Publication status | Published - 5 Mar 2013 |
Keywords
- Journal Article
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Dive into the research topics of 'Metformin-Acting through Cyclic AMP as well as AMP?'. Together they form a unique fingerprint.Projects
- 1 Finished
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Non-canonical Pathways for Regulation of AMPK (Senior Investigator Award)
Hardie, G. (Investigator)
1/04/12 → 30/09/17
Project: Research