Methotrexate combined with omalizumab for difficult to treat urticaria: a further step-up treatment?

P. Garbayo-Salmons; S. Butt; Robert S. Dawe

doi:10.1111/ced.14359

Methotrexate combined with omalizumab for difficult to treat urticaria: a further step-up treatment?

P. Garbayo-Salmons (Lead / Corresponding author), S. Butt, Robert S. Dawe

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2 Citations (Scopus)

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Abstract

Classically, chronic urticaria has been treated following a stepwise approach where Omalizumab and other immunosuppressants occupy the last step. Omalizumab and Methotrexate have both been used separately for the treatment of urticaria1,2 . We believe combination treatment with both agents is a valuable alternative for refractory chronic urticaria and other related diseases such as urticarial vasculitis. Here we report on two patients who responded to the combination treatment.

Original language	English
Pages (from-to)	350-351
Number of pages	2
Journal	Clinical and Experimental Dermatology
Volume	46
Issue number	2
Early online date	29 Jun 2020
DOIs	https://doi.org/10.1111/ced.14359
Publication status	Published - Mar 2021

ASJC Scopus subject areas

Dermatology

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10.1111/ced.14359

Author Accepted ManuscriptAccepted author manuscript, 1.82 MB

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title = "Methotrexate combined with omalizumab for difficult to treat urticaria: a further step-up treatment?",

abstract = "Classically, chronic urticaria has been treated following a stepwise approach where Omalizumab and other immunosuppressants occupy the last step. Omalizumab and Methotrexate have both been used separately for the treatment of urticaria1,2 . We believe combination treatment with both agents is a valuable alternative for refractory chronic urticaria and other related diseases such as urticarial vasculitis. Here we report on two patients who responded to the combination treatment.",

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AU - Garbayo-Salmons, P.

AU - Butt, S.

AU - Dawe, Robert S.

PY - 2021/3

Y1 - 2021/3

N2 - Classically, chronic urticaria has been treated following a stepwise approach where Omalizumab and other immunosuppressants occupy the last step. Omalizumab and Methotrexate have both been used separately for the treatment of urticaria1,2 . We believe combination treatment with both agents is a valuable alternative for refractory chronic urticaria and other related diseases such as urticarial vasculitis. Here we report on two patients who responded to the combination treatment.

AB - Classically, chronic urticaria has been treated following a stepwise approach where Omalizumab and other immunosuppressants occupy the last step. Omalizumab and Methotrexate have both been used separately for the treatment of urticaria1,2 . We believe combination treatment with both agents is a valuable alternative for refractory chronic urticaria and other related diseases such as urticarial vasculitis. Here we report on two patients who responded to the combination treatment.

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U2 - 10.1111/ced.14359

DO - 10.1111/ced.14359

M3 - Letter

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Methotrexate combined with omalizumab for difficult to treat urticaria: a further step-up treatment?

Abstract

ASJC Scopus subject areas

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