Micro-magnetic resonance imaging of avian embryos

Xiaojing Li, Jia Liu, Megan Davey, Suzanne Duce, Neema Jaberi, Gang Liu, Gemma Davidson, Seaneen Tenent, Ruth Mahood, Phoebe Brown, Craig Cunningham, Andrew Bain, Kevin Beattie, Laura McDonald, Katy Schmidt, Matthew Towers, Cheryll Tickle, Sandy Chudek

    Research output: Contribution to journalArticle

    26 Citations (Scopus)

    Abstract

    Chick embryos are useful models for probing developmental mechanisms including those involved in organogenesis. In addition to classic embryological manipulations, it is possible to test the function of molecules and genes while the embryo remains within the egg. Here we define conditions for imaging chick embryo anatomy and for visualising living quail embryos. We focus on the developing limb and describe how different tissues can be imaged using micro-magnetic resonance imaging and this information then synthesised, using a three-dimensional visualisation package, into detailed anatomy. We illustrate the potential for micro-magnetic resonance imaging to analyse phenotypic changes following chick limb manipulation. The work with the living quail embryos lays the foundations for using micro-magnetic resonance imaging as an experimental tool to follow the consequences of such manipulations over time.
    Original languageEnglish
    Pages (from-to)798-809
    Number of pages12
    JournalJournal of Anatomy
    Volume211
    Issue number6
    DOIs
    Publication statusPublished - Dec 2007

    Fingerprint

    magnetic resonance imaging
    embryo
    embryo (animal)
    Quail
    Embryonic Structures
    Magnetic Resonance Imaging
    Chick Embryo
    Anatomy
    Extremities
    chicks
    quails
    limbs (animal)
    Organogenesis
    anatomy
    limb
    Ovum
    organogenesis
    visualization
    Genes
    image analysis

    Keywords

    • Anatomy
    • Avian
    • Chick
    • Embryo
    • Limb development
    • Using micro-magnetic resonance imaging
    • Magnetic resonance imaging (MRI)
    • Quail
    • MRI

    Cite this

    Li, X., Liu, J., Davey, M., Duce, S., Jaberi, N., Liu, G., ... Chudek, S. (2007). Micro-magnetic resonance imaging of avian embryos. Journal of Anatomy, 211(6), 798-809. https://doi.org/10.1111/j.1469-7580.2007.00825.x
    Li, Xiaojing ; Liu, Jia ; Davey, Megan ; Duce, Suzanne ; Jaberi, Neema ; Liu, Gang ; Davidson, Gemma ; Tenent, Seaneen ; Mahood, Ruth ; Brown, Phoebe ; Cunningham, Craig ; Bain, Andrew ; Beattie, Kevin ; McDonald, Laura ; Schmidt, Katy ; Towers, Matthew ; Tickle, Cheryll ; Chudek, Sandy. / Micro-magnetic resonance imaging of avian embryos. In: Journal of Anatomy. 2007 ; Vol. 211, No. 6. pp. 798-809.
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    abstract = "Chick embryos are useful models for probing developmental mechanisms including those involved in organogenesis. In addition to classic embryological manipulations, it is possible to test the function of molecules and genes while the embryo remains within the egg. Here we define conditions for imaging chick embryo anatomy and for visualising living quail embryos. We focus on the developing limb and describe how different tissues can be imaged using micro-magnetic resonance imaging and this information then synthesised, using a three-dimensional visualisation package, into detailed anatomy. We illustrate the potential for micro-magnetic resonance imaging to analyse phenotypic changes following chick limb manipulation. The work with the living quail embryos lays the foundations for using micro-magnetic resonance imaging as an experimental tool to follow the consequences of such manipulations over time.",
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    author = "Xiaojing Li and Jia Liu and Megan Davey and Suzanne Duce and Neema Jaberi and Gang Liu and Gemma Davidson and Seaneen Tenent and Ruth Mahood and Phoebe Brown and Craig Cunningham and Andrew Bain and Kevin Beattie and Laura McDonald and Katy Schmidt and Matthew Towers and Cheryll Tickle and Sandy Chudek",
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    Li, X, Liu, J, Davey, M, Duce, S, Jaberi, N, Liu, G, Davidson, G, Tenent, S, Mahood, R, Brown, P, Cunningham, C, Bain, A, Beattie, K, McDonald, L, Schmidt, K, Towers, M, Tickle, C & Chudek, S 2007, 'Micro-magnetic resonance imaging of avian embryos', Journal of Anatomy, vol. 211, no. 6, pp. 798-809. https://doi.org/10.1111/j.1469-7580.2007.00825.x

    Micro-magnetic resonance imaging of avian embryos. / Li, Xiaojing; Liu, Jia; Davey, Megan; Duce, Suzanne; Jaberi, Neema; Liu, Gang; Davidson, Gemma; Tenent, Seaneen; Mahood, Ruth; Brown, Phoebe; Cunningham, Craig; Bain, Andrew; Beattie, Kevin; McDonald, Laura; Schmidt, Katy; Towers, Matthew; Tickle, Cheryll; Chudek, Sandy.

    In: Journal of Anatomy, Vol. 211, No. 6, 12.2007, p. 798-809.

    Research output: Contribution to journalArticle

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    AU - Li, Xiaojing

    AU - Liu, Jia

    AU - Davey, Megan

    AU - Duce, Suzanne

    AU - Jaberi, Neema

    AU - Liu, Gang

    AU - Davidson, Gemma

    AU - Tenent, Seaneen

    AU - Mahood, Ruth

    AU - Brown, Phoebe

    AU - Cunningham, Craig

    AU - Bain, Andrew

    AU - Beattie, Kevin

    AU - McDonald, Laura

    AU - Schmidt, Katy

    AU - Towers, Matthew

    AU - Tickle, Cheryll

    AU - Chudek, Sandy

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    PY - 2007/12

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    AB - Chick embryos are useful models for probing developmental mechanisms including those involved in organogenesis. In addition to classic embryological manipulations, it is possible to test the function of molecules and genes while the embryo remains within the egg. Here we define conditions for imaging chick embryo anatomy and for visualising living quail embryos. We focus on the developing limb and describe how different tissues can be imaged using micro-magnetic resonance imaging and this information then synthesised, using a three-dimensional visualisation package, into detailed anatomy. We illustrate the potential for micro-magnetic resonance imaging to analyse phenotypic changes following chick limb manipulation. The work with the living quail embryos lays the foundations for using micro-magnetic resonance imaging as an experimental tool to follow the consequences of such manipulations over time.

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    KW - Avian

    KW - Chick

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    KW - MRI

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