Micro-magnetic resonance imaging of avian embryos

Xiaojing Li, Jia Liu, Megan Davey, Suzanne Duce, Neema Jaberi, Gang Liu, Gemma Davidson, Seaneen Tenent, Ruth Mahood, Phoebe Brown, Craig Cunningham, Andrew Bain, Kevin Beattie, Laura McDonald, Katy Schmidt, Matthew Towers, Cheryll Tickle, Sandy Chudek

    Research output: Contribution to journalArticlepeer-review

    31 Citations (Scopus)


    Chick embryos are useful models for probing developmental mechanisms including those involved in organogenesis. In addition to classic embryological manipulations, it is possible to test the function of molecules and genes while the embryo remains within the egg. Here we define conditions for imaging chick embryo anatomy and for visualising living quail embryos. We focus on the developing limb and describe how different tissues can be imaged using micro-magnetic resonance imaging and this information then synthesised, using a three-dimensional visualisation package, into detailed anatomy. We illustrate the potential for micro-magnetic resonance imaging to analyse phenotypic changes following chick limb manipulation. The work with the living quail embryos lays the foundations for using micro-magnetic resonance imaging as an experimental tool to follow the consequences of such manipulations over time.
    Original languageEnglish
    Pages (from-to)798-809
    Number of pages12
    JournalJournal of Anatomy
    Issue number6
    Publication statusPublished - Dec 2007


    • Anatomy
    • Avian
    • Chick
    • Embryo
    • Limb development
    • Using micro-magnetic resonance imaging
    • Magnetic resonance imaging (MRI)
    • Quail
    • MRI


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