Microcontroller-based digital front-end for near-infrared spectroscopy

TY - GEN

T1 - Microcontroller-based digital front-end for near-infrared spectroscopy

AU - Giardini, Mario E.

AU - Corti, Mario

AU - Guizzetti, Giovanni Guido

AU - Lago, Paolo

AU - Gelmetti, Andrea

AU - Danese, Giovanni

PY - 2000/5/3

Y1 - 2000/5/3

N2 - Near IR Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues. Monitoring of these parameters is particularly useful both for basic research and during surgery, when a continuous and real-time measurement can help to avoid permanent damage to the tissues. We present a modular acquisition system in which each subsystem, from the case to the single acquisition front-end is designed to meet all the requirements of a research-grade instrument, dedicated to intraoperatory measurements. Part of the modules of the acquisition system has been dedicated to multipoint NIRS. A module prototype has been developed, which is able to control four LED sources and two detectors. On each front-end a RISC microcontroller performs source and detector multiplexing with a digital correlation technique. A number of such modules can be independently addressed through a bus by a PC-based workstation for data collection, processing and visualization. Preliminary test of the prototype on tourniquet-induced forearm ischemia show adequate detectivity and time response. The operating parameters derived from the prototype will be employed in the design of a high channel count module, which will exploit the capabilities of a digital signal processor, for spatially mapped brain oxygenation monitoring.

AB - Near IR Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues. Monitoring of these parameters is particularly useful both for basic research and during surgery, when a continuous and real-time measurement can help to avoid permanent damage to the tissues. We present a modular acquisition system in which each subsystem, from the case to the single acquisition front-end is designed to meet all the requirements of a research-grade instrument, dedicated to intraoperatory measurements. Part of the modules of the acquisition system has been dedicated to multipoint NIRS. A module prototype has been developed, which is able to control four LED sources and two detectors. On each front-end a RISC microcontroller performs source and detector multiplexing with a digital correlation technique. A number of such modules can be independently addressed through a bus by a PC-based workstation for data collection, processing and visualization. Preliminary test of the prototype on tourniquet-induced forearm ischemia show adequate detectivity and time response. The operating parameters derived from the prototype will be employed in the design of a high channel count module, which will exploit the capabilities of a digital signal processor, for spatially mapped brain oxygenation monitoring.

KW - Near-infrared spectroscopy

KW - NIRS

U2 - 10.1117/12.384921

DO - 10.1117/12.384921

M3 - Conference contribution

VL - 3911

T3 - Proceedings of SPIE - The International Society for Optical Engineering

SP - 338

EP - 344

BT - Biomedical Diagnostic, Guidance, and Surgical Assist Systems II

A2 - Vo-Dinh, Tuan

A2 - Grundfest, Warren S.

A2 - Benaron, David A.

PB - SPIE-International Society for Optical Engineering

T2 - BIOS 2000 The International Symposium on Biomedical Optics

Y2 - 22 January 2000 through 28 January 2000

ER -