Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging

Yuri Belotti; Michael Conneely; Tianjun Huang; Stephen McKenna; Ghulam Nabi; David McGloin

doi:10.1117/12.2284553

Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging

Yuri Belotti
, Michael Conneely
, Tianjun Huang
, Stephen McKenna
, Ghulam Nabi
, David McGloin

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We demonstrate a single channel hydrodynamic stretching microfluidic device that relies on high-speed imaging to allow repeated dynamic cell deformation measurements. Experiments on prostate cancer cells suggest richer data than current approaches.

Original language	English
Title of host publication	Novel Biophotonics Techniques and Applications IV
Editors	I. Alex Vitkin, Arjen Amelink
Place of Publication	United States
Publisher	Optical Society of America
Volume	10413
ISBN (Electronic)	9781510612846
ISBN (Print)	9781557528209
DOIs	https://doi.org/10.1117/12.2284553
Publication status	Published - 28 Jul 2017
Event	European Conference on Biomedical Optics, ECBO 2017 - Munich, Germany Duration: 25 Jun 2017 → 29 Jun 2017

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10413
ISSN (Print)	1605-7422

Conference

Conference	European Conference on Biomedical Optics, ECBO 2017
Country/Territory	Germany
City	Munich
Period	25/06/17 → 29/06/17

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

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10.1117/12.2284553

Cite this

Belotti, Y., Conneely, M., Huang, T., McKenna, S., Nabi, G., & McGloin, D. (2017). Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging. In I. A. Vitkin, & A. Amelink (Eds.), Novel Biophotonics Techniques and Applications IV (Vol. 10413). Article 1041305 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10413). Optical Society of America. https://doi.org/10.1117/12.2284553

Belotti, Yuri ; Conneely, Michael ; Huang, Tianjun et al. / Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging. Novel Biophotonics Techniques and Applications IV. editor / I. Alex Vitkin ; Arjen Amelink. Vol. 10413 United States : Optical Society of America, 2017. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

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title = "Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging",

abstract = "We demonstrate a single channel hydrodynamic stretching microfluidic device that relies on high-speed imaging to allow repeated dynamic cell deformation measurements. Experiments on prostate cancer cells suggest richer data than current approaches.",

author = "Yuri Belotti and Michael Conneely and Tianjun Huang and Stephen McKenna and Ghulam Nabi and David McGloin",

year = "2017",

month = jul,

day = "28",

doi = "10.1117/12.2284553",

language = "English",

isbn = "9781557528209",

volume = "10413",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "Optical Society of America",

editor = "Vitkin, \{I. Alex\} and Arjen Amelink",

booktitle = "Novel Biophotonics Techniques and Applications IV",

address = "United States",

note = "European Conference on Biomedical Optics, ECBO 2017 ; Conference date: 25-06-2017 Through 29-06-2017",

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Belotti, Y, Conneely, M, Huang, T, McKenna, S , Nabi, G & McGloin, D 2017, Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging. in IA Vitkin & A Amelink (eds), Novel Biophotonics Techniques and Applications IV. vol. 10413, 1041305, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10413, Optical Society of America, United States, European Conference on Biomedical Optics, ECBO 2017, Munich, Germany, 25/06/17. https://doi.org/10.1117/12.2284553

Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging. / Belotti, Yuri; Conneely, Michael; Huang, Tianjun et al.
Novel Biophotonics Techniques and Applications IV. ed. / I. Alex Vitkin; Arjen Amelink. Vol. 10413 United States: Optical Society of America, 2017. 1041305 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10413).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging

AU - Belotti, Yuri

AU - Conneely, Michael

AU - Huang, Tianjun

AU - McKenna, Stephen

AU - Nabi, Ghulam

AU - McGloin, David

PY - 2017/7/28

Y1 - 2017/7/28

N2 - We demonstrate a single channel hydrodynamic stretching microfluidic device that relies on high-speed imaging to allow repeated dynamic cell deformation measurements. Experiments on prostate cancer cells suggest richer data than current approaches.

AB - We demonstrate a single channel hydrodynamic stretching microfluidic device that relies on high-speed imaging to allow repeated dynamic cell deformation measurements. Experiments on prostate cancer cells suggest richer data than current approaches.

UR - https://www.scopus.com/pages/publications/85033675907

U2 - 10.1117/12.2284553

DO - 10.1117/12.2284553

M3 - Conference contribution

AN - SCOPUS:85033675907

SN - 9781557528209

VL - 10413

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Novel Biophotonics Techniques and Applications IV

A2 - Vitkin, I. Alex

A2 - Amelink, Arjen

PB - Optical Society of America

CY - United States

T2 - European Conference on Biomedical Optics, ECBO 2017

Y2 - 25 June 2017 through 29 June 2017

ER -

Belotti Y, Conneely M, Huang T, McKenna S , Nabi G, McGloin D. Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging. In Vitkin IA, Amelink A, editors, Novel Biophotonics Techniques and Applications IV. Vol. 10413. United States: Optical Society of America. 2017. 1041305. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2284553

Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging

Abstract

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UN SDGs

ASJC Scopus subject areas

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