Microstructure and Cell Adhesion of Hydroxyapatite/Collagen Composites

H.R. Le, S. Pranti-Haran, K. Donnelly, R.P. Keatch

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    This paper reports the development of a simple and cost effective method to fabricate hydroxyapatite/collagen nanocomposites. Hydroxyapatite is obtained by simultaneous dropping of calcium containing solution and phosphate containing solution into a reaction vessel. The microstructure of the hydroxyapatite particles exhibits a plate-like morphology under certain pH and temperature conditions. The plate-like morphology has a positive effect on the flexural strength of the composites prepared from precipitated hydroxyapatite and agarose gel. Cell adhesion tests on the precipitated hydroxyapatite and collagen indicate that the composite has excellent biocompatibility.

    Original languageEnglish
    Title of host publicationWorld Congress on Medical Physics and Biomedical Engineering, Vol 25, Pt 10
    EditorsO Dossel, WC Schlegel
    Place of PublicationNew York
    PublisherSpringer
    Pages122-125
    Number of pages4
    ISBN (Print)978-3-642-03899-0
    Publication statusPublished - 2009
    EventWorld Congress on Medical Physics and Biomedical Engineering - Munich, Germany
    Duration: 7 Sep 200912 Sep 2009
    http://conference.vde.com/world-congress-2009/Pages/Home.aspx

    Conference

    ConferenceWorld Congress on Medical Physics and Biomedical Engineering
    CountryGermany
    CityMunich
    Period7/09/0912/09/09
    Internet address

    Keywords

    • Hydroxyapatite
    • Collagen
    • Nanocomposites
    • Microstructure
    • Biocompatibility
    • SELF-ORGANIZATION MECHANISM
    • NANOCOMPOSITES
    • COLLAGEN

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