Microstructure and Cell Adhesion of Hydroxyapatite/Collagen Composites

H.R. Le; S. Pranti-Haran; K. Donnelly; R.P. Keatch

Microstructure and Cell Adhesion of Hydroxyapatite/Collagen Composites

H.R. Le, S. Pranti-Haran, K. Donnelly, R.P. Keatch

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This paper reports the development of a simple and cost effective method to fabricate hydroxyapatite/collagen nanocomposites. Hydroxyapatite is obtained by simultaneous dropping of calcium containing solution and phosphate containing solution into a reaction vessel. The microstructure of the hydroxyapatite particles exhibits a plate-like morphology under certain pH and temperature conditions. The plate-like morphology has a positive effect on the flexural strength of the composites prepared from precipitated hydroxyapatite and agarose gel. Cell adhesion tests on the precipitated hydroxyapatite and collagen indicate that the composite has excellent biocompatibility.

Original language	English
Title of host publication	World Congress on Medical Physics and Biomedical Engineering, Vol 25, Pt 10
Editors	O Dossel, WC Schlegel
Place of Publication	New York
Publisher	Springer
Pages	122-125
Number of pages	4
ISBN (Print)	978-3-642-03899-0
Publication status	Published - 2009
Event	World Congress on Medical Physics and Biomedical Engineering - Munich, Germany Duration: 7 Sept 2009 → 12 Sept 2009 http://conference.vde.com/world-congress-2009/Pages/Home.aspx

Conference

Conference	World Congress on Medical Physics and Biomedical Engineering
Country/Territory	Germany
City	Munich
Period	7/09/09 → 12/09/09
Internet address	http://conference.vde.com/world-congress-2009/Pages/Home.aspx

Keywords

Hydroxyapatite
Collagen
Nanocomposites
Microstructure
Biocompatibility
SELF-ORGANIZATION MECHANISM
NANOCOMPOSITES
COLLAGEN

Cite this

@inproceedings{48ce619e44c54689bb6e01273a4030bd,

title = "Microstructure and Cell Adhesion of Hydroxyapatite/Collagen Composites",

abstract = "This paper reports the development of a simple and cost effective method to fabricate hydroxyapatite/collagen nanocomposites. Hydroxyapatite is obtained by simultaneous dropping of calcium containing solution and phosphate containing solution into a reaction vessel. The microstructure of the hydroxyapatite particles exhibits a plate-like morphology under certain pH and temperature conditions. The plate-like morphology has a positive effect on the flexural strength of the composites prepared from precipitated hydroxyapatite and agarose gel. Cell adhesion tests on the precipitated hydroxyapatite and collagen indicate that the composite has excellent biocompatibility.",

keywords = "Hydroxyapatite, Collagen, Nanocomposites, Microstructure, Biocompatibility, SELF-ORGANIZATION MECHANISM, NANOCOMPOSITES, COLLAGEN",

author = "H.R. Le and S. Pranti-Haran and K. Donnelly and R.P. Keatch",

year = "2009",

language = "English",

isbn = "978-3-642-03899-0",

pages = "122--125",

editor = "O Dossel and WC Schlegel",

booktitle = "World Congress on Medical Physics and Biomedical Engineering, Vol 25, Pt 10",

publisher = "Springer ",

note = "World Congress on Medical Physics and Biomedical Engineering ; Conference date: 07-09-2009 Through 12-09-2009",

url = "http://conference.vde.com/world-congress-2009/Pages/Home.aspx",

}

TY - GEN

T1 - Microstructure and Cell Adhesion of Hydroxyapatite/Collagen Composites

AU - Le, H.R.

AU - Pranti-Haran, S.

AU - Donnelly, K.

AU - Keatch, R.P.

PY - 2009

Y1 - 2009

N2 - This paper reports the development of a simple and cost effective method to fabricate hydroxyapatite/collagen nanocomposites. Hydroxyapatite is obtained by simultaneous dropping of calcium containing solution and phosphate containing solution into a reaction vessel. The microstructure of the hydroxyapatite particles exhibits a plate-like morphology under certain pH and temperature conditions. The plate-like morphology has a positive effect on the flexural strength of the composites prepared from precipitated hydroxyapatite and agarose gel. Cell adhesion tests on the precipitated hydroxyapatite and collagen indicate that the composite has excellent biocompatibility.

AB - This paper reports the development of a simple and cost effective method to fabricate hydroxyapatite/collagen nanocomposites. Hydroxyapatite is obtained by simultaneous dropping of calcium containing solution and phosphate containing solution into a reaction vessel. The microstructure of the hydroxyapatite particles exhibits a plate-like morphology under certain pH and temperature conditions. The plate-like morphology has a positive effect on the flexural strength of the composites prepared from precipitated hydroxyapatite and agarose gel. Cell adhesion tests on the precipitated hydroxyapatite and collagen indicate that the composite has excellent biocompatibility.

KW - Hydroxyapatite

KW - Collagen

KW - Nanocomposites

KW - Microstructure

KW - Biocompatibility

KW - SELF-ORGANIZATION MECHANISM

KW - NANOCOMPOSITES

KW - COLLAGEN

M3 - Conference contribution

SN - 978-3-642-03899-0

SP - 122

EP - 125

BT - World Congress on Medical Physics and Biomedical Engineering, Vol 25, Pt 10

A2 - Dossel, O

A2 - Schlegel, WC

PB - Springer

CY - New York

T2 - World Congress on Medical Physics and Biomedical Engineering

Y2 - 7 September 2009 through 12 September 2009

ER -

Microstructure and Cell Adhesion of Hydroxyapatite/Collagen Composites

Abstract

Conference

Keywords

Fingerprint

Cite this