Mineralocorticoid receptor antagonists

Hari Krishnan Parthasarathy, Thomas M. MacDonald

    Research output: Contribution to journalArticle

    6 Citations (Scopus)

    Abstract

    With an increasingly aging population, the need for effective treatment of cardiovascular diseases (eg, heart failure, hypertension, and ischemic heart disease) cannot be overemphasized. The vital importance of mineralocorticoid receptor antagonists for treating cardiovascular conditions has only been appreciated in the last decade. The re-emergence of mineralocorticoid receptor antagonists has provided clinicians with an important tool towards complete blockade of the renin-angiotensin-aldosterone axis.

    Original languageEnglish
    Pages (from-to)45-52
    Number of pages8
    JournalCurrent Hypertension Reports
    Volume9
    Issue number1
    DOIs
    Publication statusPublished - Mar 2007

    Keywords

    • SELECTIVE ALDOSTERONE BLOCKER
    • LEFT-VENTRICULAR HYPERTROPHY
    • RANDOMIZED ALDACTONE EVALUATION
    • CONGESTIVE-HEART-FAILURE
    • ESSENTIAL-HYPERTENSION
    • MYOCARDIAL-INFARCTION
    • IN-VIVO
    • SPIRONOLACTONE
    • EPLERENONE
    • EFFICACY

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