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Missense variants in human ACE2 modify binding to SARS-CoV-2 Spike
Stuart A. MacGowan
, Michael I. Barton (Lead / Corresponding author)
, Mikhail Kutuzov
, Omer Dushek
, P. Anton van der Merwe
,
Geoffrey J. Barton
Computational Biology
Research output
:
Working paper/Preprint
›
Preprint
139
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Dive into the research topics of 'Missense variants in human ACE2 modify binding to SARS-CoV-2 Spike'. Together they form a unique fingerprint.
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Keyphrases
Missense Variants
100%
Angiotensin-converting Enzyme 2 (ACE2)
100%
SARS-CoV-2 Spike
100%
Surface Plasmon Resonance
25%
COVID-19
25%
GnomAD
25%
Severe Disease
12%
Distinct Population Segment
12%
Infectious Diseases
12%
Global Epidemiology
12%
Prediction Algorithms
12%
Population Distribution
12%
SARS-CoV-2 Infection
12%
Population Variants
12%
Resistance to Infection
12%
CAMS-CSM
12%
Affinity Prediction
12%
Spike Receptor Binding Domain
12%
Ashkenazi Jews
12%
Biochemistry, Genetics and Molecular Biology
Missense
100%
Spike
100%
Angiotensin-Converting Enzyme 2
100%
SARS Coronavirus
100%
Surface Plasmon Resonance
25%
Allele
12%
Binding Domain
12%
Prevalence
12%
Population Distribution
12%
Receptor Binding
12%