Missing pieces of an ancient puzzle: evolution of the Eukaryotic Membrane-Trafficking System

Alexander Schlacht; Emily K. Herman; Mary J. Klute; Mark C. Field; Joel B. Dacks

doi:10.1101/cshperspect.a016048

Missing pieces of an ancient puzzle: evolution of the Eukaryotic Membrane-Trafficking System

Alexander Schlacht, Emily K. Herman, Mary J. Klute, Mark C. Field, Joel B. Dacks (Lead / Corresponding author)

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52 Citations (Scopus)

Abstract

The membrane-trafficking system underpins cellular trafficking of material in eukaryotes and its evolution would have been a watershed in eukaryogenesis. Evolutionary cell biological studies have been unraveling the history of proteins responsible for vesicle transport and organelle identity revealing both highly conserved components and lineage-specific innovations. Recently, endomembrane components with a broad, but patchy, distribution have been observed as well, pieces that are missing from our cell biological and evolutionary models of membrane trafficking. These data together allow for new insights into the history and forces that shape the evolution of this critical cell biological system.

Original language	English
Article number	a016048
Journal	Cold spring harbor perspectives in biology
Volume	6
Issue number	10
DOIs	https://doi.org/10.1101/cshperspect.a016048
Publication status	Published - Oct 2014

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Missing pieces of an ancient puzzle: evolution of the Eukaryotic Membrane-Trafficking System

Abstract

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