Modeling Alzheimer’s disease brains in Vitro

Christopher Henstridge, Tara Spires-Jones

    Research output: Contribution to journalArticlepeer-review

    14 Citations (Scopus)

    Abstract

    Alzheimer’s disease (AD) research is hampered by a lack of models that recapitulate all key disease features. Park et al. introduce a microfluidic device containing a 3D culture of human neurons, astrocytes, and microglia that develop AD-like pathology, revealing a potentially important inflammatory mechanism of neurodegeneration.
    Original languageEnglish
    Pages (from-to)899-900
    Number of pages2
    JournalNature Neuroscience
    Volume21
    DOIs
    Publication statusPublished - 27 Jun 2018

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