Molecular and clinical investigations in patients with low-renin hypertension

Isla S. Mackenzie, Morris J. Brown

    Research output: Contribution to journalReview articlepeer-review

    13 Citations (Scopus)

    Abstract

    Interactions between the renin-angiotensin-aldosterone system and other mechanisms determining sodium balance are important in the pathophysiology of hypertension. Low-renin hypertension is a common type of resistant hypertension and is often associated with increased sodium retention. The importance of investigation, factors determining renin and aldosterone levels, and drug therapies in low-renin hypertension are reviewed.

    Original languageEnglish
    Pages (from-to)18
    Number of pages8
    JournalClinical and Experimental Nephrology
    Volume13
    Issue number1
    DOIs
    Publication statusPublished - Feb 2009

    Keywords

    • Hypertension
    • Renin
    • Aldosterone
    • Low-renin hypertension
    • CALCIUM-CHANNEL BLOCKADE
    • DOUBLE-BLIND CROSSOVER
    • PRIMARY ALDOSTERONISM
    • ANGIOTENSIN-II
    • BLOOD-PRESSURE
    • NIFEDIPINE
    • RESPONSES
    • RATIO
    • SPIRONOLACTONE
    • NICARDIPINE

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