Molecular and clinical investigations in patients with low-renin hypertension

Isla S. Mackenzie; Morris J. Brown

doi:10.1007/s10157-008-0071-4

Molecular and clinical investigations in patients with low-renin hypertension

Isla S. Mackenzie
, Morris J. Brown

Research output: Contribution to journal › Review article › peer-review

18 Citations (Scopus)

Abstract

Interactions between the renin-angiotensin-aldosterone system and other mechanisms determining sodium balance are important in the pathophysiology of hypertension. Low-renin hypertension is a common type of resistant hypertension and is often associated with increased sodium retention. The importance of investigation, factors determining renin and aldosterone levels, and drug therapies in low-renin hypertension are reviewed.

Original language	English
Pages (from-to)	18
Number of pages	8
Journal	Clinical and Experimental Nephrology
Volume	13
Issue number	1
DOIs	https://doi.org/10.1007/s10157-008-0071-4
Publication status	Published - Feb 2009

Keywords

Hypertension
Renin
Aldosterone
Low-renin hypertension
CALCIUM-CHANNEL BLOCKADE
DOUBLE-BLIND CROSSOVER
PRIMARY ALDOSTERONISM
ANGIOTENSIN-II
BLOOD-PRESSURE
NIFEDIPINE
RESPONSES
RATIO
SPIRONOLACTONE
NICARDIPINE

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10.1007/s10157-008-0071-4

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title = "Molecular and clinical investigations in patients with low-renin hypertension",

abstract = "Interactions between the renin-angiotensin-aldosterone system and other mechanisms determining sodium balance are important in the pathophysiology of hypertension. Low-renin hypertension is a common type of resistant hypertension and is often associated with increased sodium retention. The importance of investigation, factors determining renin and aldosterone levels, and drug therapies in low-renin hypertension are reviewed.",

keywords = "Hypertension, Renin, Aldosterone, Low-renin hypertension, CALCIUM-CHANNEL BLOCKADE, DOUBLE-BLIND CROSSOVER, PRIMARY ALDOSTERONISM, ANGIOTENSIN-II, BLOOD-PRESSURE, NIFEDIPINE, RESPONSES, RATIO, SPIRONOLACTONE, NICARDIPINE",

author = "Mackenzie, \{Isla S.\} and Brown, \{Morris J.\}",

year = "2009",

month = feb,

doi = "10.1007/s10157-008-0071-4",

language = "English",

volume = "13",

pages = "18",

journal = "Clinical and Experimental Nephrology",

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T1 - Molecular and clinical investigations in patients with low-renin hypertension

AU - Mackenzie, Isla S.

AU - Brown, Morris J.

PY - 2009/2

Y1 - 2009/2

N2 - Interactions between the renin-angiotensin-aldosterone system and other mechanisms determining sodium balance are important in the pathophysiology of hypertension. Low-renin hypertension is a common type of resistant hypertension and is often associated with increased sodium retention. The importance of investigation, factors determining renin and aldosterone levels, and drug therapies in low-renin hypertension are reviewed.

AB - Interactions between the renin-angiotensin-aldosterone system and other mechanisms determining sodium balance are important in the pathophysiology of hypertension. Low-renin hypertension is a common type of resistant hypertension and is often associated with increased sodium retention. The importance of investigation, factors determining renin and aldosterone levels, and drug therapies in low-renin hypertension are reviewed.

KW - Hypertension

KW - Renin

KW - Aldosterone

KW - Low-renin hypertension

KW - CALCIUM-CHANNEL BLOCKADE

KW - DOUBLE-BLIND CROSSOVER

KW - PRIMARY ALDOSTERONISM

KW - ANGIOTENSIN-II

KW - BLOOD-PRESSURE

KW - NIFEDIPINE

KW - RESPONSES

KW - RATIO

KW - SPIRONOLACTONE

KW - NICARDIPINE

U2 - 10.1007/s10157-008-0071-4

DO - 10.1007/s10157-008-0071-4

M3 - Review article

SN - 1342-1751

VL - 13

SP - 18

JO - Clinical and Experimental Nephrology

JF - Clinical and Experimental Nephrology

IS - 1

ER -

Molecular and clinical investigations in patients with low-renin hypertension

Abstract

Keywords

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