Molecular mechanism of genotoxicity of the environmental pollutant 3-nitrobenzanthrone.

Keyphrases

• Molecular Mechanism 100%
• Genotoxicity 100%
• Environmental Pollutants 100%
• 3-Nitrobenzanthrone 100%
• 3-aminobenzanthrone 70%
• DNA Adducts 40%
• Peroxidase 20%
• Liver 20%
• Phase II Enzymes 20%
• Oxidoreductase 20%
• NQO1 20%
• Phase I Enzymes 20%
• Air Pollution 10%
• Metabolism 10%
• Metabolic Flexibility 10%
• NAD(P) 10%
• Quinone Oxidoreductase 10%
• Cytochrome P450 Reductase 10%
• Cytochrome P450 1A1 (CYP1A1) 10%
• Cytochrome P450 (CYP450) 10%
• SULT1A1 10%
• Sulfotransferase 10%
• C57BL 10%
• N-acetyltransferase 2 (NAT2) 10%
• Extrahepatic Tissues 10%
• Mediated Oxidation 10%
• Extrahepatic Organs 10%
• Reactive Species 10%
• Nitroreductase 10%
• Cytoplasmic Enzyme 10%
• Myeloperoxidase 10%
• Oxidative Activation 10%
• Lactoperoxidase 10%
• Human Metabolites 10%
• Diesel Exhaust 10%
• Prostaglandin H Synthase 10%
• Human Carcinogen 10%
• SULT1A2 10%
• O-acetyltransferase 10%
• Exhaust Pollution 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Genotoxicity 100%
• 3 Nitrobenzanthrone 100%
• Oxidoreductase 20%
• Carcinogen 10%
• Reduced Nicotinamide Adenine Dinucleotide Phosphate 10%
• Synthetase 10%
• Cytochrome P450 Reductase 10%
• Cytochrome P450 10%
• Reduced Nicotinamide Adenine Dinucleotide (Phosphate) Dehydrogenase (Quinone) 10%
• Cytochrome P450 1A1 10%
• Sulfotransferase 10%
• C57BL 6 Mouse 10%
• Nitroreductase 10%
• Acyltransferase 10%
• Myeloperoxidase 10%
• Prostaglandin H 10%
• Lactoperoxidase 10%