Monthly swelling of the knee - Case report and review of the literature

Jetse Jelsma (Lead / Corresponding author), Alistair Mayne, Bjorn Steffanie

    Research output: Contribution to journalReview articlepeer-review

    3 Citations (Scopus)


    Introduction: We report a 17-year old with monthly swelling of her knee. The complaints are associated with the menstrual cycle. After physical examination, radiographs, MRI and an arthroscopy with biopsies, a diagnosis of intra-articular endometriosis and menstrual arthritis was made.

    Discussion: Both an intra-articular manifestation of endometriosis and menstrual arthritis are very rare diagnoses. Extraperitoneal lesions of endometriosis are rare and the mechanism for spreading outside the retroperitoneal space is unknown. A similar situation exists for menstrual arthritis, it is thought that cytokines, which are produced as a reaction to retrograde menstruation, are the trigger for menstrual arthritis. A review of literature is given.

    Conclusion: A monthly recurrent, painful swelling of a joint, can and should give rise to thorough investigation. Differential diagnostic one should think of intra-articular manifestation of endometriosis and menstrual arthritis. We give a proposal for treatment.

    Original languageEnglish
    Pages (from-to)559-560
    Number of pages2
    Issue number3
    Early online date10 Feb 2016
    Publication statusPublished - Jun 2016


    • Monthly knee pain
    • Endometriosis
    • Menstrual arthritis


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