Mornitoring High Intensity Focused Ultrasound (HIFU) Treatment Using Optical Coherence Tomography: Feasibility Study

Research output: Chapter in Book/Report/Conference proceedingConference contribution

121 Downloads (Pure)

Abstract

HIFU is a noninvasive, acoustic therapeutic technique that utilizes high intensity acoustic field in the ultrasound focus to kill the targeted tissue for disease treatment purpose. The feasibility of monitoring and guiding HIFU treatment using the optical property change in the superficial area of biological tissue is explored. Ex-vivo bovine liver tissue was treated using different HIFU doses (same energy level for Os, 1s, 5s, 9s) in this research. The 3D structure volume and elastogram were acquired in the lesion area after HIFU treatment. The OCT structure images clearly show the boundary of HIFU lesion area and surrounding normal tissue, even for 1s treatment time, which agree well with the elastography results. The average OCT signal intensity and OCT signal attenuation ratio in the lesion area grows as the treatment time increases. Combined with OCT needle probe, the proposed method has a large potential not only to be used for superficial diseases treatment monitoring, but also to be used for high-precision-demanded diseases treatment monitoring, e.g. nervous disease treatment monitoring.

Original languageEnglish
Title of host publication2018 IEEE International Ultrasonics Symposium, IUS 2018
PublisherIEEE Computer Society
Number of pages4
Volume2018-October
ISBN (Electronic)9781538634257
ISBN (Print)9781538634264
DOIs
Publication statusPublished - 20 Dec 2018
Event2018 IEEE International Ultrasonics Symposium, IUS 2018 - Kobe, Japan
Duration: 22 Oct 201825 Oct 2018

Publication series

Name
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2018 IEEE International Ultrasonics Symposium, IUS 2018
CountryJapan
CityKobe
Period22/10/1825/10/18

Keywords

  • ex-vivo bovine liver
  • high intensity focused ultrasound (HIFU)
  • optical coherence tomography
  • optical property
  • shear wave elastography
  • treatment monitoring

Fingerprint Dive into the research topics of 'Mornitoring High Intensity Focused Ultrasound (HIFU) Treatment Using Optical Coherence Tomography: Feasibility Study'. Together they form a unique fingerprint.

  • Cite this

    Zhou, K., Wang, Y., Wang, G., Feng, K., Li, F., Li, C., & Huang, Z. (2018). Mornitoring High Intensity Focused Ultrasound (HIFU) Treatment Using Optical Coherence Tomography: Feasibility Study. In 2018 IEEE International Ultrasonics Symposium, IUS 2018 (Vol. 2018-October). [8580088] IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2018.8580088