Mortality and hospital stay associated with resistant Staphylococcus aureus and Escherichia coli bacteremia: estimating the burden of antibiotic resistance in Europe

Marlieke E A de Kraker (Lead / Corresponding author), Peter G Davey, Hajo Grundmann, BURDEN Study Group

    Research output: Contribution to journalArticle

    325 Citations (Scopus)

    Abstract

    The relative importance of human diseases is conventionally assessed by cause-specific mortality, morbidity, and economic impact. Current estimates for infections caused by antibiotic-resistant bacteria are not sufficiently supported by quantitative empirical data. This study determined the excess number of deaths, bed-days, and hospital costs associated with blood stream infections (BSIs) caused by methicillin-resistant Staphylococcus aureus (MRSA) and third-generation cephalosporin-resistant Escherichia coli (G3CREC) in 31 countries that participated in the European Antimicrobial Resistance Surveillance System (EARSS).
    Original languageEnglish
    Pages (from-to)e1001104
    JournalPLoS Medicine
    Volume8
    Issue number10
    DOIs
    Publication statusPublished - 2011

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