Mortality and hospital stay associated with resistant Staphylococcus aureus and Escherichia coli bacteremia

estimating the burden of antibiotic resistance in Europe

Marlieke E A de Kraker (Lead / Corresponding author), Peter G Davey, Hajo Grundmann, BURDEN Study Group

    Research output: Contribution to journalArticle

    279 Citations (Scopus)

    Abstract

    The relative importance of human diseases is conventionally assessed by cause-specific mortality, morbidity, and economic impact. Current estimates for infections caused by antibiotic-resistant bacteria are not sufficiently supported by quantitative empirical data. This study determined the excess number of deaths, bed-days, and hospital costs associated with blood stream infections (BSIs) caused by methicillin-resistant Staphylococcus aureus (MRSA) and third-generation cephalosporin-resistant Escherichia coli (G3CREC) in 31 countries that participated in the European Antimicrobial Resistance Surveillance System (EARSS).
    Original languageEnglish
    Pages (from-to)e1001104
    JournalPLoS Medicine
    Volume8
    Issue number10
    DOIs
    Publication statusPublished - 2011

    Fingerprint

    Microbial Drug Resistance
    Bacteremia
    Staphylococcus aureus
    Length of Stay
    Escherichia coli
    Mortality
    Hospital Costs
    Cephalosporins
    Methicillin-Resistant Staphylococcus aureus
    Infection
    Economics
    Anti-Bacterial Agents
    Morbidity
    Bacteria

    Cite this

    @article{fbde94c3d2ac45c1962af830a836b530,
    title = "Mortality and hospital stay associated with resistant Staphylococcus aureus and Escherichia coli bacteremia: estimating the burden of antibiotic resistance in Europe",
    abstract = "The relative importance of human diseases is conventionally assessed by cause-specific mortality, morbidity, and economic impact. Current estimates for infections caused by antibiotic-resistant bacteria are not sufficiently supported by quantitative empirical data. This study determined the excess number of deaths, bed-days, and hospital costs associated with blood stream infections (BSIs) caused by methicillin-resistant Staphylococcus aureus (MRSA) and third-generation cephalosporin-resistant Escherichia coli (G3CREC) in 31 countries that participated in the European Antimicrobial Resistance Surveillance System (EARSS).",
    author = "{de Kraker}, {Marlieke E A} and Davey, {Peter G} and Hajo Grundmann and {BURDEN Study Group}",
    year = "2011",
    doi = "10.1371/journal.pmed.1001104",
    language = "English",
    volume = "8",
    pages = "e1001104",
    journal = "PLoS Medicine",
    issn = "1549-1277",
    publisher = "Public Library of Science",
    number = "10",

    }

    Mortality and hospital stay associated with resistant Staphylococcus aureus and Escherichia coli bacteremia : estimating the burden of antibiotic resistance in Europe. / de Kraker, Marlieke E A (Lead / Corresponding author); Davey, Peter G; Grundmann, Hajo; BURDEN Study Group.

    In: PLoS Medicine, Vol. 8, No. 10, 2011, p. e1001104.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Mortality and hospital stay associated with resistant Staphylococcus aureus and Escherichia coli bacteremia

    T2 - estimating the burden of antibiotic resistance in Europe

    AU - de Kraker, Marlieke E A

    AU - Davey, Peter G

    AU - Grundmann, Hajo

    AU - BURDEN Study Group

    PY - 2011

    Y1 - 2011

    N2 - The relative importance of human diseases is conventionally assessed by cause-specific mortality, morbidity, and economic impact. Current estimates for infections caused by antibiotic-resistant bacteria are not sufficiently supported by quantitative empirical data. This study determined the excess number of deaths, bed-days, and hospital costs associated with blood stream infections (BSIs) caused by methicillin-resistant Staphylococcus aureus (MRSA) and third-generation cephalosporin-resistant Escherichia coli (G3CREC) in 31 countries that participated in the European Antimicrobial Resistance Surveillance System (EARSS).

    AB - The relative importance of human diseases is conventionally assessed by cause-specific mortality, morbidity, and economic impact. Current estimates for infections caused by antibiotic-resistant bacteria are not sufficiently supported by quantitative empirical data. This study determined the excess number of deaths, bed-days, and hospital costs associated with blood stream infections (BSIs) caused by methicillin-resistant Staphylococcus aureus (MRSA) and third-generation cephalosporin-resistant Escherichia coli (G3CREC) in 31 countries that participated in the European Antimicrobial Resistance Surveillance System (EARSS).

    UR - http://www.scopus.com/inward/record.url?scp=80055031553&partnerID=8YFLogxK

    U2 - 10.1371/journal.pmed.1001104

    DO - 10.1371/journal.pmed.1001104

    M3 - Article

    VL - 8

    SP - e1001104

    JO - PLoS Medicine

    JF - PLoS Medicine

    SN - 1549-1277

    IS - 10

    ER -