Mortality and hospital stay associated with resistant Staphylococcus aureus and Escherichia coli bacteremia: estimating the burden of antibiotic resistance in Europe

TY - JOUR

T1 - Mortality and hospital stay associated with resistant Staphylococcus aureus and Escherichia coli bacteremia

T2 - estimating the burden of antibiotic resistance in Europe

AU - de Kraker, Marlieke E A

AU - Davey, Peter G

AU - Grundmann, Hajo

AU - BURDEN Study Group

PY - 2011

Y1 - 2011

N2 - The relative importance of human diseases is conventionally assessed by cause-specific mortality, morbidity, and economic impact. Current estimates for infections caused by antibiotic-resistant bacteria are not sufficiently supported by quantitative empirical data. This study determined the excess number of deaths, bed-days, and hospital costs associated with blood stream infections (BSIs) caused by methicillin-resistant Staphylococcus aureus (MRSA) and third-generation cephalosporin-resistant Escherichia coli (G3CREC) in 31 countries that participated in the European Antimicrobial Resistance Surveillance System (EARSS).

AB - The relative importance of human diseases is conventionally assessed by cause-specific mortality, morbidity, and economic impact. Current estimates for infections caused by antibiotic-resistant bacteria are not sufficiently supported by quantitative empirical data. This study determined the excess number of deaths, bed-days, and hospital costs associated with blood stream infections (BSIs) caused by methicillin-resistant Staphylococcus aureus (MRSA) and third-generation cephalosporin-resistant Escherichia coli (G3CREC) in 31 countries that participated in the European Antimicrobial Resistance Surveillance System (EARSS).

UR - https://www.scopus.com/pages/publications/80055031553

U2 - 10.1371/journal.pmed.1001104

DO - 10.1371/journal.pmed.1001104

M3 - Article

C2 - 22022233

SN - 1549-1277

VL - 8

SP - e1001104

JO - PLoS Medicine

JF - PLoS Medicine

IS - 10

ER -