Motion tracing system for ultrasound guided HIFU

Xu Xiao, Tingyi Jiang, George Corner, Zhihong Huang

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

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    One main limitation in HIFU treatment is the abdominal movement in liver and kidney caused by respiration. The study has set up a tracking model which mainly compromises of a target carrying box and a motion driving balloon. A real-time B-mode ultrasound guidance method suitable for tracking of the abdominal organ motion in 2D was established and tested. For the setup, the phantoms mimicking moving organs are carefully prepared with agar surrounding round-shaped egg-white as the target of focused ultrasound ablation. Physiological phantoms and animal tissues are driven moving reciprocally along the main axial direction of the ultrasound image probe with slightly motion perpendicular to the axial direction. The moving speed and range could be adjusted by controlling the inflation and deflation speed and amount of the balloon driven by a medical ventilator. A 6-DOF robotic arm was used to position the focused ultrasound transducer. The overall system was trying to estimate to simulate the actual movement caused by human respiration. HIFU ablation experiments using phantoms and animal organs were conducted to test the tracking effect. Ultrasound strain elastography was used to post estimate the efficiency of the tracking algorithms and system. In moving state, the axial size of the lesion (perpendicular to the movement direction) are averagely 4mm, which is one third larger than the lesion got when the target was not moving. This presents the possibility of developing a low-cost real-time method of tracking organ motion during HIFU treatment in liver or kidney.

    Original languageEnglish
    Title of host publicationProceedings from the 13th International Symposium on Therapeutic Ultrasound
    PublisherAIP Publishing
    ISBN (Electronic)9780735414846
    Publication statusPublished - 1 Mar 2017
    Event13th International Symposium on Therapeutic Ultrasound, ISTU 2013 - Shanghai, China
    Duration: 12 May 201315 May 2013


    Conference13th International Symposium on Therapeutic Ultrasound, ISTU 2013

    ASJC Scopus subject areas

    • Physics and Astronomy(all)


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