MR-compatible assistance system for biopsy in a high-field-strength system: initial results in patients with suspicious prostate lesions

Stephan Zangos; Andreas Melzer; Katrin Eichler; Cyrus Sadighi; Axel Thalhammer; Boris Bodelle; Renate Wolf; Tatjana Gruber-Rouh; Dirk Proschek; Renate Hammerstingl; Cindy Mueller; Martin G. Mack; Thomas J. Vogl

doi:10.1148/radiol.11101559

MR-compatible assistance system for biopsy in a high-field-strength system: initial results in patients with suspicious prostate lesions

Stephan Zangos, Andreas Melzer, Katrin Eichler, Cyrus Sadighi, Axel Thalhammer, Boris Bodelle, Renate Wolf, Tatjana Gruber-Rouh, Dirk Proschek, Renate Hammerstingl, Cindy Mueller, Martin G. Mack, Thomas J. Vogl

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Abstract

Purpose: To examine the feasibility and safety of magnetic resonance (MR)-guided biopsy by using a transgluteal approach in patients with suspicious prostate lesions by using an MR-compatible robotic system and a 1.5-T MR system.

Materials and Methods: The study was approved by the institutional review board of University Frankfurt, and informed consent was obtained from each patient. A total of 20 patients (age range, 57.8-71.9 years; mean age, 65.1 years) underwent biopsy in a closed-bore high-field-strength MR system. Biopsy was performed with an MR-compatible pneumatically driven robotic system. T1-weighted gradient-echo fast low-angle shot and T2-weighted true fast imaging with steady-state precession sequences were used to plan and guide the intervention with a transgluteal access on the external planning computer of the assistance system. The system calculated the trajectory and then moved the guiding arm to the insertion point. The cannula was advanced manually, and biopsies were performed with the coaxial technique by using a 15-gauge pencil tip needle. Intervention time, complications, and biopsy findings were documented.

Results: The MR-compatible robotic system did not interfere with image quality, nor did MR imaging cause dysfunction of the robot. In one patient, the interventionist caused a fail-safe system shutdown. This was due to inadvertent displacement of the guiding arm during cannula insertion. This problem was solved by increasing the displacement threshold. Accurate coaxial cannula biopsy could be performed in all subsequent patients. Sufficient histopathologic assessment was performed in 19 patients. Insufficient material was retrieved in the patient who experienced fail-safe system shutdown. The median intervention time was 39 minutes (23-65 minutes). No procedure-related complications were observed.

Conclusion: Preliminary results indicate that MR-guided robot-assisted biopsy is feasible and can be performed safely with highly accurate cannula placement. (C) RSNA, 2011

Original language	English
Pages (from-to)	903-910
Number of pages	8
Journal	Radiology
Volume	259
Issue number	3
Early online date	1 Mar 2011
DOIs	https://doi.org/10.1148/radiol.11101559
Publication status	Published - Jun 2011

Keywords

Transgluteal biopsies
Antigen levels
Cancer
Feasability
Device
Interventions
Validation
Navigation
Placement

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1148/radiol.11101559

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Zangos, S., Melzer, A., Eichler, K., Sadighi, C., Thalhammer, A., Bodelle, B., Wolf, R., Gruber-Rouh, T., Proschek, D., Hammerstingl, R., Mueller, C., Mack, M. G., & Vogl, T. J. (2011). MR-compatible assistance system for biopsy in a high-field-strength system: initial results in patients with suspicious prostate lesions. Radiology, 259(3), 903-910. https://doi.org/10.1148/radiol.11101559

@article{e2c0242391bd455daf52c597a5fff61f,

title = "MR-compatible assistance system for biopsy in a high-field-strength system: initial results in patients with suspicious prostate lesions",

abstract = "Purpose: To examine the feasibility and safety of magnetic resonance (MR)-guided biopsy by using a transgluteal approach in patients with suspicious prostate lesions by using an MR-compatible robotic system and a 1.5-T MR system.Materials and Methods: The study was approved by the institutional review board of University Frankfurt, and informed consent was obtained from each patient. A total of 20 patients (age range, 57.8-71.9 years; mean age, 65.1 years) underwent biopsy in a closed-bore high-field-strength MR system. Biopsy was performed with an MR-compatible pneumatically driven robotic system. T1-weighted gradient-echo fast low-angle shot and T2-weighted true fast imaging with steady-state precession sequences were used to plan and guide the intervention with a transgluteal access on the external planning computer of the assistance system. The system calculated the trajectory and then moved the guiding arm to the insertion point. The cannula was advanced manually, and biopsies were performed with the coaxial technique by using a 15-gauge pencil tip needle. Intervention time, complications, and biopsy findings were documented.Results: The MR-compatible robotic system did not interfere with image quality, nor did MR imaging cause dysfunction of the robot. In one patient, the interventionist caused a fail-safe system shutdown. This was due to inadvertent displacement of the guiding arm during cannula insertion. This problem was solved by increasing the displacement threshold. Accurate coaxial cannula biopsy could be performed in all subsequent patients. Sufficient histopathologic assessment was performed in 19 patients. Insufficient material was retrieved in the patient who experienced fail-safe system shutdown. The median intervention time was 39 minutes (23-65 minutes). No procedure-related complications were observed.Conclusion: Preliminary results indicate that MR-guided robot-assisted biopsy is feasible and can be performed safely with highly accurate cannula placement. (C) RSNA, 2011",

keywords = "Transgluteal biopsies, Antigen levels, Cancer, Feasability, Device, Interventions, Validation, Navigation, Placement",

author = "Stephan Zangos and Andreas Melzer and Katrin Eichler and Cyrus Sadighi and Axel Thalhammer and Boris Bodelle and Renate Wolf and Tatjana Gruber-Rouh and Dirk Proschek and Renate Hammerstingl and Cindy Mueller and Mack, {Martin G.} and Vogl, {Thomas J.}",

year = "2011",

month = jun,

doi = "10.1148/radiol.11101559",

language = "English",

volume = "259",

pages = "903--910",

journal = "Radiology",

issn = "0033-8419",

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Zangos, S, Melzer, A, Eichler, K, Sadighi, C, Thalhammer, A, Bodelle, B, Wolf, R, Gruber-Rouh, T, Proschek, D, Hammerstingl, R, Mueller, C, Mack, MG & Vogl, TJ 2011, 'MR-compatible assistance system for biopsy in a high-field-strength system: initial results in patients with suspicious prostate lesions', Radiology, vol. 259, no. 3, pp. 903-910. https://doi.org/10.1148/radiol.11101559

TY - JOUR

T1 - MR-compatible assistance system for biopsy in a high-field-strength system

T2 - initial results in patients with suspicious prostate lesions

AU - Zangos, Stephan

AU - Melzer, Andreas

AU - Eichler, Katrin

AU - Sadighi, Cyrus

AU - Thalhammer, Axel

AU - Bodelle, Boris

AU - Wolf, Renate

AU - Gruber-Rouh, Tatjana

AU - Proschek, Dirk

AU - Hammerstingl, Renate

AU - Mueller, Cindy

AU - Mack, Martin G.

AU - Vogl, Thomas J.

PY - 2011/6

Y1 - 2011/6

N2 - Purpose: To examine the feasibility and safety of magnetic resonance (MR)-guided biopsy by using a transgluteal approach in patients with suspicious prostate lesions by using an MR-compatible robotic system and a 1.5-T MR system.Materials and Methods: The study was approved by the institutional review board of University Frankfurt, and informed consent was obtained from each patient. A total of 20 patients (age range, 57.8-71.9 years; mean age, 65.1 years) underwent biopsy in a closed-bore high-field-strength MR system. Biopsy was performed with an MR-compatible pneumatically driven robotic system. T1-weighted gradient-echo fast low-angle shot and T2-weighted true fast imaging with steady-state precession sequences were used to plan and guide the intervention with a transgluteal access on the external planning computer of the assistance system. The system calculated the trajectory and then moved the guiding arm to the insertion point. The cannula was advanced manually, and biopsies were performed with the coaxial technique by using a 15-gauge pencil tip needle. Intervention time, complications, and biopsy findings were documented.Results: The MR-compatible robotic system did not interfere with image quality, nor did MR imaging cause dysfunction of the robot. In one patient, the interventionist caused a fail-safe system shutdown. This was due to inadvertent displacement of the guiding arm during cannula insertion. This problem was solved by increasing the displacement threshold. Accurate coaxial cannula biopsy could be performed in all subsequent patients. Sufficient histopathologic assessment was performed in 19 patients. Insufficient material was retrieved in the patient who experienced fail-safe system shutdown. The median intervention time was 39 minutes (23-65 minutes). No procedure-related complications were observed.Conclusion: Preliminary results indicate that MR-guided robot-assisted biopsy is feasible and can be performed safely with highly accurate cannula placement. (C) RSNA, 2011

AB - Purpose: To examine the feasibility and safety of magnetic resonance (MR)-guided biopsy by using a transgluteal approach in patients with suspicious prostate lesions by using an MR-compatible robotic system and a 1.5-T MR system.Materials and Methods: The study was approved by the institutional review board of University Frankfurt, and informed consent was obtained from each patient. A total of 20 patients (age range, 57.8-71.9 years; mean age, 65.1 years) underwent biopsy in a closed-bore high-field-strength MR system. Biopsy was performed with an MR-compatible pneumatically driven robotic system. T1-weighted gradient-echo fast low-angle shot and T2-weighted true fast imaging with steady-state precession sequences were used to plan and guide the intervention with a transgluteal access on the external planning computer of the assistance system. The system calculated the trajectory and then moved the guiding arm to the insertion point. The cannula was advanced manually, and biopsies were performed with the coaxial technique by using a 15-gauge pencil tip needle. Intervention time, complications, and biopsy findings were documented.Results: The MR-compatible robotic system did not interfere with image quality, nor did MR imaging cause dysfunction of the robot. In one patient, the interventionist caused a fail-safe system shutdown. This was due to inadvertent displacement of the guiding arm during cannula insertion. This problem was solved by increasing the displacement threshold. Accurate coaxial cannula biopsy could be performed in all subsequent patients. Sufficient histopathologic assessment was performed in 19 patients. Insufficient material was retrieved in the patient who experienced fail-safe system shutdown. The median intervention time was 39 minutes (23-65 minutes). No procedure-related complications were observed.Conclusion: Preliminary results indicate that MR-guided robot-assisted biopsy is feasible and can be performed safely with highly accurate cannula placement. (C) RSNA, 2011

KW - Transgluteal biopsies

KW - Antigen levels

KW - Cancer

KW - Feasability

KW - Device

KW - Interventions

KW - Validation

KW - Navigation

KW - Placement

U2 - 10.1148/radiol.11101559

DO - 10.1148/radiol.11101559

M3 - Article

C2 - 21364080

SN - 0033-8419

VL - 259

SP - 903

EP - 910

JO - Radiology

JF - Radiology

IS - 3

ER -

MR-compatible assistance system for biopsy in a high-field-strength system: initial results in patients with suspicious prostate lesions

Abstract

Keywords

UN SDGs

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