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MR Enhancing Implants

  • Andreas Melzer (Lead / Corresponding author)
  • , Erwin Immel
  • , Richard Boyd
  • , Daniel Wendt

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

    Abstract

    Implantation of cardiovascular implants such as stents, prosthetic heart valves or vena cava filters (VCF) are usually performed using X-ray-based imaging techniques (fluoroscopy) in a cath lab. Possible migration and intraluminal changes in the implants require a post interventional follow-up diagnostic procedure. For example, restenosis (up to 25 %) and late in-stent thrombosis (up to 2 % by in drug-eluting stents and despite dual anti-platelet therapy with aspirin and thienopyridine up to 6 % in diabetes patients) frequently occur after the implantation of a vascular stent. Vena cava filter is by nature subject of thrombus capturing. For explantation and retrieval, it must be assured that no large blood clot formations are still present in the filter. Prosthetic heart valves and the recently introduced balloon and self-expanding heart valves for transapical and TAVI procedure require follow-up imaging of possible complications such as paravalvular leakages, valve thrombosis or malfunction of the valve leaflets which are made of bovine pericardium or porcine heart valves. Therefore, post interventional non-invasive follow-up diagnostic is needed. Transthoracic ultrasound (TUS) is the method of choice for routine follow-up but due to the sound scattering at the valve scaffold, diagnosis is compromised. More thorough diagnosis can be achieved by invasive techniques such as transesophageal endoscopic ultrasound (TEE) or intravascular ultrasound (IVUS) reveals more information but still the sound scattering leaves gaps in the diagnoses of valve function. X-ray-based invasive imaging with iodinated contrast agents can be applied but the disadvantage of this diagnostic method is, additional to the ionising radiation, adverse reactions to iodinated contrast agents. This includes general (acute and delayed) and organ-specific adverse effects (contrast-induced nephrotoxicity and cardiovascular, pulmonary and neurotoxicity) and occurs, for example, in 17–35 % of patients with history of previous adverse reaction (some of the predisposing factors for an adverse reaction are: infants and elderly, history of asthma or allergy, dehydration and heart disease).

    Original languageEnglish
    Title of host publicationIntraoperative Imaging and Image-Guided Therapy
    EditorsFerence A. Jolesz
    Place of PublicationNew York
    PublisherSpringer New York
    Chapter55
    Pages725-737
    Number of pages13
    Edition1
    ISBN (Electronic)9781461476573
    ISBN (Print)9781461476566
    DOIs
    Publication statusPublished - 2014

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • Heart Valve
    • Larmor Frequency
    • Prosthetic Heart Valve
    • Radio Frequency Pulse
    • Resonant Circuit

    ASJC Scopus subject areas

    • General Medicine
    • General Health Professions

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