Multiple unbiased approaches identify oxidosqualene cyclase as the molecular target of a promising anti-leishmanial

Search results

• Finished

  Wellcome Centre for Anti-Infectives Research

  Baragana, B. (Investigator), Cook, S. (Investigator), De Rycker, M. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator), Lee, M. (Investigator), Pawlowic, M. C. (Investigator), Read, K. (Investigator), Wyatt, P. (Investigator) & Wyllie, S. (Investigator)

  1/04/17 → 1/04/25

  Project: Research

  • Parasite 100%
  • Trypanosoma Cruzi 81%
  • Drug Discovery 78%
  • Trypanosoma Cruzi (T. cruzi) 64%
  • Chagas Disease 59%

• Chemical Biology: Leveraging Phenotypic Hits Against Kinetoplastids (Strategic Grant)

  Fairlamb, A. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator) & Wyatt, P. (Investigator)

  1/01/15 → 31/12/20

  Project: Research

  • Parasite 100%
  • Visceral Leishmaniasis 83%
  • Drug Discovery 77%
  • Antitrypanosomal 74%
  • Chagas Disease 67%

• Protein Glycosylation in Trypanosomes: Defining and Exploiting a Biological System (Senior Investigator Award)

  Ferguson, M. (Investigator)

  1/10/13 → 30/06/23

  Project: Research

  • Trypanosoma Brucei 100%
  • Parasite 45%
  • GPI Anchor 44%
  • Polysaccharide 37%
  • Trypanosoma 34%