N-linked oligosaccharides during human renal organogenesis

S. Fleming

N-linked oligosaccharides during human renal organogenesis

S. Fleming

Research output: Contribution to journal › Article › peer-review

Abstract

The structure of fucosylated derivatives of N-acetyl lactosamine expressed during human renal development has been studied by the combined use of monoclonal antibodies and glycosyl hydrolases. LeX is expressed on the ureteric bud ampulla carried N-linked on a glycoprotein. It is also present in the proximal tubule as a ganglioside. H-Type II substance is expressed on the endothelium of the developing renal vasculature. It is also carried N-linked to a glycoprotein. These regulated changes in the cell surface carbohydrate expression are important in understanding cell interactions and receptor systems during renal development.

Original language	English
Pages (from-to)	151-160
Number of pages	10
Journal	Journal of Anatomy
Volume	170
Publication status	Published - 1990

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Fleming, S. (1990). N-linked oligosaccharides during human renal organogenesis. Journal of Anatomy, 170, 151-160. http://www.scopus.com/results/results.url?sort=plf-f&src=s&st1=N-linked+oligosaccharides+during+human+renal+organogenesis&sid=3E474EBD3E949E93DC775820D5BA1F57.y7ESLndDIsN8cE7qwvy6w%3a90&sot=b&sdt=b&sl=73&s=TITLE-ABS-KEY%28N-linked+oligosaccharides+during+human+renal+organogenesis%29&origin=searchbasic&txGid=3E474EBD3E949E93DC775820D5BA1F57.y7ESLndDIsN8cE7qwvy6w%3a9

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title = "N-linked oligosaccharides during human renal organogenesis",

abstract = "The structure of fucosylated derivatives of N-acetyl lactosamine expressed during human renal development has been studied by the combined use of monoclonal antibodies and glycosyl hydrolases. LeX is expressed on the ureteric bud ampulla carried N-linked on a glycoprotein. It is also present in the proximal tubule as a ganglioside. H-Type II substance is expressed on the endothelium of the developing renal vasculature. It is also carried N-linked to a glycoprotein. These regulated changes in the cell surface carbohydrate expression are important in understanding cell interactions and receptor systems during renal development.",

author = "S. Fleming",

year = "1990",

language = "English",

volume = "170",

pages = "151--160",

journal = "Journal of Anatomy",

issn = "0021-8782",

publisher = "Wiley",

}

Fleming, S 1990, 'N-linked oligosaccharides during human renal organogenesis', Journal of Anatomy, vol. 170, pp. 151-160. <http://www.scopus.com/results/results.url?sort=plf-f&src=s&st1=N-linked+oligosaccharides+during+human+renal+organogenesis&sid=3E474EBD3E949E93DC775820D5BA1F57.y7ESLndDIsN8cE7qwvy6w%3a90&sot=b&sdt=b&sl=73&s=TITLE-ABS-KEY%28N-linked+oligosaccharides+during+human+renal+organogenesis%29&origin=searchbasic&txGid=3E474EBD3E949E93DC775820D5BA1F57.y7ESLndDIsN8cE7qwvy6w%3a9>

TY - JOUR

T1 - N-linked oligosaccharides during human renal organogenesis

AU - Fleming, S.

PY - 1990

Y1 - 1990

N2 - The structure of fucosylated derivatives of N-acetyl lactosamine expressed during human renal development has been studied by the combined use of monoclonal antibodies and glycosyl hydrolases. LeX is expressed on the ureteric bud ampulla carried N-linked on a glycoprotein. It is also present in the proximal tubule as a ganglioside. H-Type II substance is expressed on the endothelium of the developing renal vasculature. It is also carried N-linked to a glycoprotein. These regulated changes in the cell surface carbohydrate expression are important in understanding cell interactions and receptor systems during renal development.

AB - The structure of fucosylated derivatives of N-acetyl lactosamine expressed during human renal development has been studied by the combined use of monoclonal antibodies and glycosyl hydrolases. LeX is expressed on the ureteric bud ampulla carried N-linked on a glycoprotein. It is also present in the proximal tubule as a ganglioside. H-Type II substance is expressed on the endothelium of the developing renal vasculature. It is also carried N-linked to a glycoprotein. These regulated changes in the cell surface carbohydrate expression are important in understanding cell interactions and receptor systems during renal development.

M3 - Article

C2 - 1701421

SN - 0021-8782

VL - 170

SP - 151

EP - 160

JO - Journal of Anatomy

JF - Journal of Anatomy

ER -

N-linked oligosaccharides during human renal organogenesis

Abstract

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