Nanoconjugates of CdTe@ZnS quantum dots with cobalt tetraamino-phthalocyanine: Characterization and implications for the fluorescence recognition of superoxide anion

Oluwasesan Adegoke; Edith Antunes; Tebello Nyokong

doi:10.1016/j.jphotochem.2013.02.010

Nanoconjugates of CdTe@ZnS quantum dots with cobalt tetraamino-phthalocyanine: Characterization and implications for the fluorescence recognition of superoxide anion

Oluwasesan Adegoke, Edith Antunes, Tebello Nyokong (Lead / Corresponding author)

Leverhulme Research Centre for Forensic Science

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

The covalent linking of thiol-capped CdTe@ZnS QDs with cobalt tetraamino-phthalocyanine (CoTAPc) has been successfully carried out. Several techniques such as time-resolved fluorescence measurements, thermal gravimetric analysis, transmission electron microscopy and spectrophotometric techniques were employed to characterize the nanoconjugates. Covalent binding of the QDs with CoTAPc resulted in the fluorescence quenching of the former. In the presence of varying concentrations of superoxide anion (O2−), the fluorescence of the QDs in the conjugate was gradually enhanced and the detection limits obtained were 2.1 and 2.4 nM for the smaller and larger QDs, respectively. Based on the excellent selectivity displayed by the nanoconjugates towards O2− over other biologically active species, a potential nanosensor was developed.

Original language	English
Pages (from-to)	11-19
Number of pages	9
Journal	Journal of Photochemistry and Photobiology A: Chemistry
Volume	257
Early online date	21 Feb 2013
DOIs	https://doi.org/10.1016/j.jphotochem.2013.02.010
Publication status	Published - 1 Apr 2013

Keywords

Superoxide anion
Cobalt tetraamino-phthalocyanines
Quantum dots
Fluorescence

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10.1016/j.jphotochem.2013.02.010

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title = "Nanoconjugates of CdTe@ZnS quantum dots with cobalt tetraamino-phthalocyanine: Characterization and implications for the fluorescence recognition of superoxide anion",

abstract = "The covalent linking of thiol-capped CdTe@ZnS QDs with cobalt tetraamino-phthalocyanine (CoTAPc) has been successfully carried out. Several techniques such as time-resolved fluorescence measurements, thermal gravimetric analysis, transmission electron microscopy and spectrophotometric techniques were employed to characterize the nanoconjugates. Covalent binding of the QDs with CoTAPc resulted in the fluorescence quenching of the former. In the presence of varying concentrations of superoxide anion (O2−), the fluorescence of the QDs in the conjugate was gradually enhanced and the detection limits obtained were 2.1 and 2.4 nM for the smaller and larger QDs, respectively. Based on the excellent selectivity displayed by the nanoconjugates towards O2− over other biologically active species, a potential nanosensor was developed.",

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doi = "10.1016/j.jphotochem.2013.02.010",

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Nanoconjugates of CdTe@ZnS quantum dots with cobalt tetraamino-phthalocyanine: Characterization and implications for the fluorescence recognition of superoxide anion. / Adegoke, Oluwasesan; Antunes, Edith; Nyokong, Tebello (Lead / Corresponding author).
In: Journal of Photochemistry and Photobiology A: Chemistry, Vol. 257, 01.04.2013, p. 11-19.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Nanoconjugates of CdTe@ZnS quantum dots with cobalt tetraamino-phthalocyanine

T2 - Characterization and implications for the fluorescence recognition of superoxide anion

AU - Adegoke, Oluwasesan

AU - Antunes, Edith

AU - Nyokong, Tebello

PY - 2013/4/1

Y1 - 2013/4/1

N2 - The covalent linking of thiol-capped CdTe@ZnS QDs with cobalt tetraamino-phthalocyanine (CoTAPc) has been successfully carried out. Several techniques such as time-resolved fluorescence measurements, thermal gravimetric analysis, transmission electron microscopy and spectrophotometric techniques were employed to characterize the nanoconjugates. Covalent binding of the QDs with CoTAPc resulted in the fluorescence quenching of the former. In the presence of varying concentrations of superoxide anion (O2−), the fluorescence of the QDs in the conjugate was gradually enhanced and the detection limits obtained were 2.1 and 2.4 nM for the smaller and larger QDs, respectively. Based on the excellent selectivity displayed by the nanoconjugates towards O2− over other biologically active species, a potential nanosensor was developed.

AB - The covalent linking of thiol-capped CdTe@ZnS QDs with cobalt tetraamino-phthalocyanine (CoTAPc) has been successfully carried out. Several techniques such as time-resolved fluorescence measurements, thermal gravimetric analysis, transmission electron microscopy and spectrophotometric techniques were employed to characterize the nanoconjugates. Covalent binding of the QDs with CoTAPc resulted in the fluorescence quenching of the former. In the presence of varying concentrations of superoxide anion (O2−), the fluorescence of the QDs in the conjugate was gradually enhanced and the detection limits obtained were 2.1 and 2.4 nM for the smaller and larger QDs, respectively. Based on the excellent selectivity displayed by the nanoconjugates towards O2− over other biologically active species, a potential nanosensor was developed.

KW - Superoxide anion

KW - Cobalt tetraamino-phthalocyanines

KW - Quantum dots

KW - Fluorescence

U2 - 10.1016/j.jphotochem.2013.02.010

DO - 10.1016/j.jphotochem.2013.02.010

M3 - Article

SN - 1010-6030

VL - 257

SP - 11

EP - 19

JO - Journal of Photochemistry and Photobiology A: Chemistry

JF - Journal of Photochemistry and Photobiology A: Chemistry

ER -

Nanoconjugates of CdTe@ZnS quantum dots with cobalt tetraamino-phthalocyanine: Characterization and implications for the fluorescence recognition of superoxide anion

Abstract

Keywords

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