Projects per year
Video capsule endoscopy (VCE) has become a clinically accepted diagnostic modality in the last 20 years and has established a technological roadmap for other capsule endoscopy (CE) devices, incorporating microscale technology, a local power supply and wireless communication. However, VCE does not provide a therapeutic function and research in therapeutic capsule endoscopy (TCE) has been limited. This paper proposes a new route towards viable TCE based on multiple CE devices including essential nanoscale components. A first device is used for multimodal diagnosis, with quantitative microultrasound as a complement to video imaging. Ultrasound-enhanced fluorescent marking of sites of pathology allows follow-up with a second device for therapy. This is based on fluorescence imaging and ultrasound-mediated targeted drug delivery. Subsequent treatment verification and monitoring with a third device exploits the minimally invasive nature of CE. Clinical implementation of a complete patient pathway remains the subject of research but several key components have been prepared in early prototype form. These are described, along with gaps that remain to be filled.
|Title of host publication||2017 IEEE 17th International Conference on Nanotechnology, NANO 2017|
|Place of Publication||United States|
|Number of pages||2|
|Publication status||Published - 23 Nov 2017|
|Event||17th IEEE International Conference on Nanotechnology, NANO 2017 - Pittsburgh, United States|
Duration: 25 Jul 2017 → 28 Jul 2017
|Conference||17th IEEE International Conference on Nanotechnology, NANO 2017|
|Period||25/07/17 → 28/07/17|
- Nanoscale devices
- Ultrasonic imaging
FingerprintDive into the research topics of 'Nanotechnology in multimodal theranostic capsule endoscopy'. Together they form a unique fingerprint.
- 1 Finished
Sonopill: Minimally Invasive Gastrointestinal Diagnosis and Therapy (Joint with University of Glasgow & Heriot Watt University)
27/05/13 → 14/12/18