National implementation of multi-parametric magnetic resonance imaging for prostate cancer detection – recommendations from a UK consensus meeting

Mrishta Brizmohun Appayya, Jim Adshead, Hashim U. Ahmed, Clare Allen, Alan Bainbridge, Tristan Barrett, Francesco Giganti, John Graham, Phil Haslam, Edward W. Johnston, Christof Kastner, Alexander P. S. Kirkham, Alexandra Lipton, Alan McNeill, Larissa Moniz, Caroline M. Moore, Ghulam Nabi, Anwar R. Padhani, Chris Parker, Amit PatelJacqueline Pursey, Jonathan Richenberg, John Staffurth, Jan van der Meulen, Darren Walls, Shonit Punwani (Lead / Corresponding author)

    Research output: Contribution to journalArticlepeer-review

    106 Citations (Scopus)
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    Objectives: To identify areas of agreement and disagreement in the implementation of multi-parametric MRI (mpMRI) of the prostate in the diagnostic pathway.

    Materials and Methods: Fifteen UK experts in prostate mpMRI and/or prostate cancer management across the UK (involving 9 NHS centres to provide for geographical spread) participated in a consensus meeting following the UCLA-RAND Appropriateness Method, and were moderated by an independent chair. The experts considered 354 items pertaining to who can request an mpMRI, prostate mpMRI protocol, reporting guidelines, training, quality assurance (QA) and patient management based on mpMRI levels of suspicion for cancer. Each item was rated for agreement on a 9-point scale. A panel median score of >/= 7 constituted 'agreement' for an item; for an item to reach 'consensus', a panel majority scoring was required.

    Results: Consensus was reached on 59% of items (208/354); these were used to provide recommendations for the implementation of prostate mpMRI in the UK. Key findings include prostate mpMRI requests should be made in consultation with the urological team; mpMRI scanners should undergo quality assurance checks to guarantee consistently high diagnostic quality scans; scans should only be reported by trained and experienced radiologists to ensure that men with non-suspicious prostate mpMRI might consider avoiding an immediate biopsy.

    Conclusions: Our consensus statements demonstrate a set of criteria that are required for the practical dissemination of consistently high quality prostate mpMRI as a diagnostic test prior to biopsy in men at risk.

    Original languageEnglish
    Pages (from-to)13-25
    Number of pages13
    JournalBJU International
    Issue number1
    Early online date26 Apr 2018
    Publication statusPublished - 1 Jul 2018


    • consensus methods
    • multi-parametric MRI
    • prostate cancer
    • recommendations

    ASJC Scopus subject areas

    • Urology


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