Neurovasculature of high and low tie ligation of the inferior mesenteric artery

Amy Campbell (Lead / Corresponding author), Angus MacDonald, Raymond Oliphant, David Russell, Quentin A. Fogg

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)
181 Downloads (Pure)


Purpose: Controversy exists as to whether a high or low tie ligation of the inferior mesenteric artery (IMA) is the preferred technique in surgeries of the left colon and rectum. This study aims to contribute to the discussion as to which is the more beneficial technique by investigating the neurovasculature at each site.

Methods: Ten embalmed cadaveric donors underwent division of the inferior mesenteric artery at the level of the low tie. The artery was subsequently ligated at the root to render a section of tissue for histological analysis of the proximal (high tie), mid and distal (low tie) segments.

Results: Ganglia observed in the proximal end of seven specimens in the sample imply that there would be disruption to the
innervation in a high tie procedure.

Conclusion: This study suggests that a high tie should be avoided if the low tie is oncologically viable.
Original languageEnglish
Pages (from-to)1343-1348
Number of pages6
JournalSurgical and Radiologic Anatomy
Issue number12
Early online date1 Sept 2018
Publication statusPublished - 1 Dec 2018


  • High tie
  • Histology
  • Inferior mesenteric artery
  • Low tie
  • Neurovasculature

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging


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