New mechanical recanalization devices - the future in pediatric stroke treatment

TY - JOUR

T1 - New mechanical recanalization devices - the future in pediatric stroke treatment

AU - Grunwald, Iris Quasar

AU - Walter, Silke

AU - Shamdeen, Mohammed Ghiath

AU - Dautermann, Anna

AU - Roth, Christian

AU - Haass, Anton

AU - Bolar, Linet Jenifa

AU - Reith, Wolfgang

AU - Kühn, Anna Luisa

AU - Papanagiotou, Panagiotis

PY - 2010/2

Y1 - 2010/2

N2 - Objective: To evaluate the recanalization rate and clinical outcome in children with acute ischemic stroke following treatment with innovative mechanical thrombectomy devices. Patients and methods: Three subjects aged 7-16 years presenting with acute cerebral vascular occlusions (thrombolysis in myocardial infarction [TIMI] 0) were treated with either the Penumbra System, operating on an aspiration platform, or the Phenox clot retriever device, a flexible wire compound with perpendicularly-oriented polyamid microfilaments. Target vessels were the internal carotid artery, the middle cerebral artery and the basilar artery. Results: Successful recanalization (TIMI 3) was attained in all cases. No device-related complications or intracranial hemorrhage occurred. Follow up was conducted for up to 30 days. A 10- to 26-point improvement in the National Institutes of Health Stroke Scale (NIHSS) score was achieved. Conclusions: Mechanical thrombectomy devices possess a dual advantage whereby they can achieve instant recanalization as well as minimize the number of bleeds that customarily accompany intravenous and intra-arterial therapy. These new devices could contribute greatly to treatment decisions in a field not yet clearly defined by current guidelines.

AB - Objective: To evaluate the recanalization rate and clinical outcome in children with acute ischemic stroke following treatment with innovative mechanical thrombectomy devices. Patients and methods: Three subjects aged 7-16 years presenting with acute cerebral vascular occlusions (thrombolysis in myocardial infarction [TIMI] 0) were treated with either the Penumbra System, operating on an aspiration platform, or the Phenox clot retriever device, a flexible wire compound with perpendicularly-oriented polyamid microfilaments. Target vessels were the internal carotid artery, the middle cerebral artery and the basilar artery. Results: Successful recanalization (TIMI 3) was attained in all cases. No device-related complications or intracranial hemorrhage occurred. Follow up was conducted for up to 30 days. A 10- to 26-point improvement in the National Institutes of Health Stroke Scale (NIHSS) score was achieved. Conclusions: Mechanical thrombectomy devices possess a dual advantage whereby they can achieve instant recanalization as well as minimize the number of bleeds that customarily accompany intravenous and intra-arterial therapy. These new devices could contribute greatly to treatment decisions in a field not yet clearly defined by current guidelines.

UR - https://pubmed.ncbi.nlm.nih.gov/20124590/

M3 - Article

SN - 1042-3931

VL - 22

SP - 63

EP - 66

JO - Journal of Invasive Cardiology

JF - Journal of Invasive Cardiology

IS - 2

ER -