Non-Contrast MRI Methods as a Tool for the Pre-Operative Assessment and Surveillance of the Arterio-Venous Fistula for Haemodialysis

Conor Macdonald, Stephen Gandy, E C M Avison, Shona Matthew, Rose Ross, John Houston

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)
158 Downloads (Pure)


Objective: To compare non-contrast enhanced MRI with ultrasound (US) for measurement of arm blood vessel geometries and flow velocities in volunteers and patients with end-stage renal disease. Materials and Methods: Subjects were scanned using US (reference standard), and MRI 2D Time of Flight (ToF), 2D Phase Contrast (PC), and 3D multi-echo data image combination (MEDIC). Patients were also scanned after arteriovenous fistula (AVF) surgery. Results: For mean vessel diameters (radial and brachial arteries; cephalic vein) MEDIC measurements were similar to US (p>0.05). However, ToF underestimated the mean diameter of the cephalic vein relative to US (p <0.05). For arterial velocity measurements, the mean values derived by PC-MR and US were similar (p>0.05). Post- operatively the intra-luminal signal intensity was hypo-intense at the anastomosis site using ToF and MEDIC. At the same site the outer boundary of the vessel was consistently lost on ToF, but remained clearly delineated on the MEDIC images. Discussion: With the exception of ToF, the MRI data demonstrated excellent agreement with US for measurements of vessel geometry and flow velocity. Further, the ability to clearly delineate the post-surgery vessel edges with MEDIC MRI suggests that the technique may be useful for surveillance after AVF creation or for patient-specific modelling studies.
Original languageEnglish
Pages (from-to)735-745
Number of pages11
JournalMagnetic Resonance Materials in Physics, Biology and Medicine (Magma)
Issue number6
Early online date21 Aug 2018
Publication statusPublished - 1 Dec 2018


  • MRI
  • Ultrasound
  • Arterio-venous fistula
  • Humans

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Biophysics
  • Radiology Nuclear Medicine and imaging


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