Non-opioid-based adjuvant analgesia in perioperative care

Shankar Ramaswamy, John A. Wilson (Lead / Corresponding author), Lesley Colvin

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)


Key points

• Perioperative pain can result in hyperalgesia, central sensitization, and ultimately chronic postsurgical pain.

• Multimodal analgesia may improve pain management, decrease opioid requirement and possibly opioid-related side-effects.

• Atypical analgesics, more often used in chronic pain, are increasingly used as for acute pain control.

• Ketamine, pregabalin, gabapentin, i.v. lidocaine, and α2 agonists have some evidence of efficacy in the perioperative setting.

• The risk–benefits of these adjuvant drugs should be carefully considered in each case.
Original languageEnglish
Pages (from-to)152-157
Number of pages6
JournalContinuing Education in Anaesthesia, Critical Care and Pain
Issue number5
Publication statusPublished - Oct 2013


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