Abstract
Key points
• Perioperative pain can result in hyperalgesia, central sensitization, and ultimately chronic postsurgical pain.
• Multimodal analgesia may improve pain management, decrease opioid requirement and possibly opioid-related side-effects.
• Atypical analgesics, more often used in chronic pain, are increasingly used as for acute pain control.
• Ketamine, pregabalin, gabapentin, i.v. lidocaine, and α2 agonists have some evidence of efficacy in the perioperative setting.
• The risk–benefits of these adjuvant drugs should be carefully considered in each case.
• Perioperative pain can result in hyperalgesia, central sensitization, and ultimately chronic postsurgical pain.
• Multimodal analgesia may improve pain management, decrease opioid requirement and possibly opioid-related side-effects.
• Atypical analgesics, more often used in chronic pain, are increasingly used as for acute pain control.
• Ketamine, pregabalin, gabapentin, i.v. lidocaine, and α2 agonists have some evidence of efficacy in the perioperative setting.
• The risk–benefits of these adjuvant drugs should be carefully considered in each case.
| Original language | English |
|---|---|
| Pages (from-to) | 152-157 |
| Number of pages | 6 |
| Journal | Continuing Education in Anaesthesia, Critical Care and Pain |
| Volume | 13 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Oct 2013 |
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine