Non-opioid-based adjuvant analgesia in perioperative care

TY - JOUR

T1 - Non-opioid-based adjuvant analgesia in perioperative care

AU - Ramaswamy, Shankar

AU - Wilson, John A.

AU - Colvin, Lesley

PY - 2013/10

Y1 - 2013/10

N2 - Key points • Perioperative pain can result in hyperalgesia, central sensitization, and ultimately chronic postsurgical pain. • Multimodal analgesia may improve pain management, decrease opioid requirement and possibly opioid-related side-effects. • Atypical analgesics, more often used in chronic pain, are increasingly used as for acute pain control. • Ketamine, pregabalin, gabapentin, i.v. lidocaine, and α2 agonists have some evidence of efficacy in the perioperative setting. • The risk–benefits of these adjuvant drugs should be carefully considered in each case.

AB - Key points • Perioperative pain can result in hyperalgesia, central sensitization, and ultimately chronic postsurgical pain. • Multimodal analgesia may improve pain management, decrease opioid requirement and possibly opioid-related side-effects. • Atypical analgesics, more often used in chronic pain, are increasingly used as for acute pain control. • Ketamine, pregabalin, gabapentin, i.v. lidocaine, and α2 agonists have some evidence of efficacy in the perioperative setting. • The risk–benefits of these adjuvant drugs should be carefully considered in each case.

UR - https://www.scopus.com/pages/publications/84893597104

U2 - 10.1093/bjaceaccp/mkt012

DO - 10.1093/bjaceaccp/mkt012

M3 - Article

AN - SCOPUS:84893597104

SN - 1743-1816

VL - 13

SP - 152

EP - 157

JO - Continuing Education in Anaesthesia, Critical Care and Pain

JF - Continuing Education in Anaesthesia, Critical Care and Pain

IS - 5

ER -