Non-steroidal anti-inflammatory drugs and complicated diverticular disease: a case-control study

K. Campbell, R. J. C. Steele

    Research output: Contribution to journalArticlepeer-review

    111 Citations (Scopus)

    Abstract

    Fifty patients with severe complications of diverticular disease were compared with two groups of 50 controls, matched for age and sex. The first control group (A) was randomly selected from all emergency hospital admissions, and the second group (B) from patients with uncomplicated diverticular disease. Of the 50 study patients, 24 (48 per cent) were taking non-steroidal anti-inflammatory drugs (NSAIDs) at the time of admission compared with nine (18 per cent) of control group A and ten (20 per cent) of control group B. Both of these differences were statistically significant, indicating a strong association between the ingestion of NSAIDs and the development of severe complications of diverticular disease.
    Original languageEnglish
    Pages (from-to)190-191
    Number of pages2
    JournalBritish Journal of Surgery
    Volume78
    Issue number2
    DOIs
    Publication statusPublished - Feb 1991

    Keywords

    • Abscess
    • Adult
    • Aged
    • Aged, 80 and over
    • Anti-Inflammatory Agents, Non-Steroidal
    • Case-Control Studies
    • Colonic Diseases
    • Diverticulum, Colon
    • Female
    • Gastrointestinal Hemorrhage
    • Humans
    • Intestinal Fistula
    • Male
    • Middle Aged
    • Peritonitis

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