Nosocomial infections and resistance pattern of common bacterial isolates in an intensive care unit of a tertiary hospital in Nigeria: A 4-year review

Garba Iliyasu, Farouq Muhammad Daiyab, Abdulwasiu Bolaji Tiamiyu, Salisu Abubakar, Zaiyad Garba Habib, Adamu Muhammad Sarki, Abdulrazaq Garba Habib

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    13 Citations (Scopus)

    Abstract

    Introduction: Infection is a major determinant of clinical outcome among patients in the intensive care unit. However, these data are lacking in most developing countries; hence, we set out to describe the profile of nosocomial infection in one of the major tertiary hospitals in northern Nigeria. Method: Case records of patients who were admitted into the intensive care unit over a 4-year period were retrospectively reviewed. A preformed questionnaire was administered, and data on clinical and microbiological profile of patients with documented infection were obtained. Results: Eighty-our episodes of nosocomial infections were identified in 76 patients. Road traffic accident (29/76, 38.2%) was the leading cause of admission. The most common infections were skin and soft tissue infections (30/84, 35.7%) followed by urinary tract infection (23/84, 27.4%). The most frequent isolates were Staphylococcus aureus (35/84, 41.7%), Klebsiella pneumoniae (18/84, 21.4%), and Escherichia coli (13/84, 15.5%). High rate of resistance to cloxacillin (19/35, 54.3%) and cotrimoxazole (17/26, 65.4%) was noted among the S aureus isolates. All the Enterobacteriaceae isolates were susceptible to meropenem, whereas resistance rate to ceftriaxone was high (E coli, 55.6%; K pneumoniae, 71.4%; Proteus spp, 50%). Conclusion: Infection control practice and measures to curtail the emergence of antimicrobial resistance need to be improved.

    Original languageEnglish
    Pages (from-to)116-120
    Number of pages5
    JournalJournal of Critical Care
    Volume34
    DOIs
    Publication statusPublished - 1 Aug 2016

    Keywords

    • Antimicrobial resistance
    • ICU
    • Nigeria
    • Nosocomial infection

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