Not hysteria: Ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis

R. Roberts, N.J.J. MacDougall, P. O'Brien, K. Abdelaziz, J. Christie, R. Swingler

    Research output: Contribution to journalArticle

    3 Citations (Scopus)

    Abstract

    We report a case of a 33-year-old nulliparous woman who, following a short prodromal illness, experienced a series of psychiatric and behavioural symptoms. These included states of terror, insomnia, delirium, self-harm and suicidal ideation, facial dyskinesias, verbigeration, cognitive impairment, reduced responsiveness, violence and paranoia. A diagnosis of anti-N-methyl-D-aspartate (NMDAR) encephalitis was made 50 days after symptom onset. Early tumour removal is associated with an improved prognosis and a laparoscopic oophorectomy was performed following detection of a dermoid cyst. Within 24 hours of the operation there was marked improvement in cognitive function and appetite.
    Original languageEnglish
    JournalScottish Medical Journal
    Volume57
    Issue number3
    DOIs
    Publication statusPublished - 2012

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    Roberts, R., MacDougall, N. J. J., O'Brien, P., Abdelaziz, K., Christie, J., & Swingler, R. (2012). Not hysteria: Ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis. Scottish Medical Journal, 57(3). https://doi.org/10.1258/smj.2012.012026