Not hysteria: Ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis

R. Roberts; N.J.J. MacDougall; P. O'Brien; K. Abdelaziz; J. Christie; R. Swingler

doi:10.1258/smj.2012.012026

Not hysteria: Ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis

R. Roberts
, N.J.J. MacDougall
, P. O'Brien
, K. Abdelaziz
, J. Christie
, R. Swingler

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

We report a case of a 33-year-old nulliparous woman who, following a short prodromal illness, experienced a series of psychiatric and behavioural symptoms. These included states of terror, insomnia, delirium, self-harm and suicidal ideation, facial dyskinesias, verbigeration, cognitive impairment, reduced responsiveness, violence and paranoia. A diagnosis of anti-N-methyl-D-aspartate (NMDAR) encephalitis was made 50 days after symptom onset. Early tumour removal is associated with an improved prognosis and a laparoscopic oophorectomy was performed following detection of a dermoid cyst. Within 24 hours of the operation there was marked improvement in cognitive function and appetite.

Original language	English
Journal	Scottish Medical Journal
Volume	57
Issue number	3
DOIs	https://doi.org/10.1258/smj.2012.012026
Publication status	Published - 2012

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 16 Peace, Justice and Strong Institutions

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10.1258/smj.2012.012026

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abstract = "We report a case of a 33-year-old nulliparous woman who, following a short prodromal illness, experienced a series of psychiatric and behavioural symptoms. These included states of terror, insomnia, delirium, self-harm and suicidal ideation, facial dyskinesias, verbigeration, cognitive impairment, reduced responsiveness, violence and paranoia. A diagnosis of anti-N-methyl-D-aspartate (NMDAR) encephalitis was made 50 days after symptom onset. Early tumour removal is associated with an improved prognosis and a laparoscopic oophorectomy was performed following detection of a dermoid cyst. Within 24 hours of the operation there was marked improvement in cognitive function and appetite.",

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AU - O'Brien, P.

AU - Abdelaziz, K.

AU - Christie, J.

AU - Swingler, R.

PY - 2012

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AB - We report a case of a 33-year-old nulliparous woman who, following a short prodromal illness, experienced a series of psychiatric and behavioural symptoms. These included states of terror, insomnia, delirium, self-harm and suicidal ideation, facial dyskinesias, verbigeration, cognitive impairment, reduced responsiveness, violence and paranoia. A diagnosis of anti-N-methyl-D-aspartate (NMDAR) encephalitis was made 50 days after symptom onset. Early tumour removal is associated with an improved prognosis and a laparoscopic oophorectomy was performed following detection of a dermoid cyst. Within 24 hours of the operation there was marked improvement in cognitive function and appetite.

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JO - Scottish Medical Journal

JF - Scottish Medical Journal

IS - 3

ER -

Not hysteria: Ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis

Abstract

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