Novel actions of leptin in the hippocampus

Jenni Harvey

doi:10.1080/07853890310008251

Novel actions of leptin in the hippocampus

Jenni Harvey (Lead / Corresponding author)

Research output: Contribution to journal › Review article › peer-review

31 Citations (Scopus)

Abstract

It is well established that the obese gene product, leptin is an important circulating satiety factor that signals nutritional status to specific hypothalamic nuclei involved in body weight regulation. However, evidence is accumulating that, in addition to its pivotal role as an adiposity signal, leptin is a multi-faceted hormone that plays an important role in a plethora of CNS functions. In this review we summarize the recent advances made in leptin biology, with particular focus on its potential role as a cognitive enhancer and antiepileptic agent in the hippocampus.

Original language	English
Pages (from-to)	197-206
Number of pages	10
Journal	Annals of Medicine
Volume	35
Issue number	3
DOIs	https://doi.org/10.1080/07853890310008251
Publication status	Published - 9 Jul 2003

Keywords

Epilepsy
Hippocampus
Leptin
Satiety signal
Synaptic plasticity

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10.1080/07853890310008251

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