DNA is highly organized spatially, both within domains of chromatin along each chromosome and within the nucleus as a whole. Recent studies suggest that chromatin localization can affect transcriptional and replicational activity. The similarity between the movements of chromatin nuclear bodies suggests a common mechanism that regulates nuclear dynamics.
|Article number||reviews0002.1 (2001)|
|Number of pages||7|
|Publication status||Published - 10 Apr 2001|