Nuclear dynamics: Where genes are and how they got there

J. R. Swedlow; A. I. Lamond

Nuclear dynamics: Where genes are and how they got there

J. R. Swedlow (Lead / Corresponding author)
, A. I. Lamond

Research output: Contribution to journal › Review article › peer-review

Abstract

DNA is highly organized spatially, both within domains of chromatin along each chromosome and within the nucleus as a whole. Recent studies suggest that chromatin localization can affect transcriptional and replicational activity. The similarity between the movements of chromatin nuclear bodies suggests a common mechanism that regulates nuclear dynamics.

Original language	English
Article number	reviews0002.1 (2001)
Number of pages	7
Journal	Genome Biology
Volume	2
Issue number	3
Publication status	Published - 10 Apr 2001

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

Cite this

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title = "Nuclear dynamics: Where genes are and how they got there",

abstract = "DNA is highly organized spatially, both within domains of chromatin along each chromosome and within the nucleus as a whole. Recent studies suggest that chromatin localization can affect transcriptional and replicational activity. The similarity between the movements of chromatin nuclear bodies suggests a common mechanism that regulates nuclear dynamics.",

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T2 - Where genes are and how they got there

AU - Swedlow, J. R.

AU - Lamond, A. I.

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N2 - DNA is highly organized spatially, both within domains of chromatin along each chromosome and within the nucleus as a whole. Recent studies suggest that chromatin localization can affect transcriptional and replicational activity. The similarity between the movements of chromatin nuclear bodies suggests a common mechanism that regulates nuclear dynamics.

AB - DNA is highly organized spatially, both within domains of chromatin along each chromosome and within the nucleus as a whole. Recent studies suggest that chromatin localization can affect transcriptional and replicational activity. The similarity between the movements of chromatin nuclear bodies suggests a common mechanism that regulates nuclear dynamics.

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UR - http://genomebiology.com/2001/2/3/reviews/0002

M3 - Review article

C2 - 11276427

AN - SCOPUS:0035087415

SN - 1465-6906

VL - 2

JO - Genome Biology

JF - Genome Biology

IS - 3

M1 - reviews0002.1 (2001)

ER -

Nuclear dynamics: Where genes are and how they got there

Abstract

ASJC Scopus subject areas

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