Nuclear organization of pre-mRNA splicing factors

Judith E. Sleeman, Angus I. Lamond (Lead / Corresponding author)

    Research output: Contribution to journalReview article

    78 Citations (Scopus)

    Abstract

    The splicing of mRNA precursors (pre-mRNA) in the nucleus is catalyzed by a complex machinery termed the spliceosome. In order to understand how it functions in vivo, it is essential to complement biochemical analyses with a detailed study of how spliceosome components are organized within the nucleus.

    Original languageEnglish
    Pages (from-to)372-377
    Number of pages6
    JournalCurrent Opinion in Cell Biology
    Volume11
    Issue number3
    DOIs
    Publication statusPublished - Jun 1999

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