Okadaic acid: a new probe for the study of cellular regulation

Philip Cohen; Charles F.B. Holmes; Yasumasa Tsukitani

doi:10.1016/0968-0004(90)90192-E

Okadaic acid: a new probe for the study of cellular regulation

Philip Cohen, Charles F.B. Holmes, Yasumasa Tsukitani

Research output: Contribution to journal › Review article › peer-review

1400 Citations (Scopus)

Abstract

The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins.

Original language	English
Pages (from-to)	98-102
Number of pages	5
Journal	Trends in Biochemical Sciences
Volume	15
Issue number	3
DOIs	https://doi.org/10.1016/0968-0004(90)90192-E
Publication status	Published - Mar 1990

ASJC Scopus subject areas

Biochemistry
Molecular Biology

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title = "Okadaic acid: a new probe for the study of cellular regulation",

abstract = "The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins.",

author = "Philip Cohen and Holmes, {Charles F.B.} and Yasumasa Tsukitani",

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Okadaic acid: a new probe for the study of cellular regulation

Abstract

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