Omaveloxolone (Skyclarys^TM) for patients with Friedreich's ataxia

Search results

• Active

  The Effect Of Malaria Parasites On Dendritic Cell Metabolism (TEMPODM) (joint with University of Glasgow)

  Dinkova-Kostova, A.

  Biotechnology and Biological Sciences Research Council

  1/04/23 → 31/03/26

  Project: Research

• The Role of Nrf2 in the Tumour Microenvironment of IDH Wild-Type Glioma (Joint with University of Edinburgh)

  Dinkova-Kostova, A.

  Medical Research Council

  1/11/22 → 31/10/25

  Project: Research

  • Tumor Microenvironment 100%
  • Metabolic 78%
  • Neurodegenerative Diseases 55%
  • NF-E2 Transcription Factor 51%
  • Oxidative Stress 47%

• Defining the Oxidative Stress-Related Mechanisms by which Activation of the Transcription Factor Nrf2 Arrests and Resolves Liver Fibrosis

  Arthur, S., Dillon, J., Dinkova-Kostova, A., Hayes, J. & Henderson, C.

  Medical Research Council

  1/04/20 → 30/06/25

  Project: Research

  • Oxidative Stress 100%
  • NF-E2-Related Factor 2 53%
  • Basic-Leucine Zipper Transcription Factors 51%
  • Ubiquitin-Protein Ligases 42%
  • Transcription Factors 36%
• Finished

  A Fully Integrated FLIM-FRET System For Imaging Dynamic Protein - Protein Interactions And Protein Turnover In Single Live Cells And Model Organisms

  Appleton, P., Dinkova-Kostova, A., Hiom, K., Januschke, J., MacDonald, M., Saurin, A., Swedlow, J., Tanaka, T. & Weijer, K.

  Biotechnology and Biological Sciences Research Council

  1/11/20 → 31/03/21

  Project: Research

  • Drosophila 100%
  • Protein 92%
  • Kelch-Like ECH-Associated Protein 1 86%
  • induced pluripotent stem cells 83%
  • Dermatological 80%

• The Assessment of Bioenergetic Dysfunction in Chronic Disease

  Ashford, M., Cantley, J. & McNeilly, A.

  1/11/20 → 31/10/22

  Project: Research

  • Kelch-Like ECH-Associated Protein 1 100%
  • Lung Neoplasms 37%
  • Protein 25%
  • NF-E2 Transcription Factor 25%
  • Silencing RNA 20%