OME-NGFF: a next-generation file format for expanding bioimaging data access strategies

Josh Moore, Christopher Allan, Sebastien Besson, Jean-Marie Burel, Erin Diel, David Gault, Kevin Kozlowski, Dominik Lindner, Melissa Linkert, Trevor Manz, William Moore, Constantin Pape, Christian Tischer, Jason R. Swedlow (Lead / Corresponding author)

    Research output: Contribution to journalArticlepeer-review

    53 Citations (Scopus)
    66 Downloads (Pure)


    The rapid pace of innovation in biological imaging and the diversity of its applications have prevented the establishment of a community-agreed standardized data format. We propose that complementing established open formats such as OME-TIFF and HDF5 with a next-generation file format such as Zarr will satisfy the majority of use cases in bioimaging. Critically, a common metadata format used in all these vessels can deliver truly findable, accessible, interoperable and reusable bioimaging data.

    Original languageEnglish
    Pages (from-to)1496-1498
    Number of pages3
    JournalNature Methods
    Early online date29 Nov 2021
    Publication statusPublished - Dec 2021


    • Computational platforms and environments
    • Data publication and archiving

    ASJC Scopus subject areas

    • Biotechnology
    • Biochemistry
    • Molecular Biology
    • Cell Biology


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