On the TRAIL to truth, or on a road to nowhere?

Maurice A. M. van Steensel (Lead / Corresponding author)

    Research output: Contribution to journalComment/debatepeer-review

    3 Citations (Scopus)
    206 Downloads (Pure)


    In this issue of Experimental Dermatology, dr. Melnik presents the hypothesis that acne is caused by inappropriate survival of cells in the sebaceous duct and gland. He proposes in particular that TRAIL mediated apoptosis is inhibited by ductal hypoxia. If it works out, this intriguing idea would suggest interesting new therapies. In my comment, I offer a critical appraisal - the TRAIL to acne pathogenesis might be rather different from what dr. Melnik would have us believe. This article is protected by copyright. All rights reserved.

    Original languageEnglish
    Pages (from-to)225-226
    Number of pages2
    JournalExperimental Dermatology
    Issue number3
    Early online date7 Oct 2016
    Publication statusPublished - 8 Mar 2017


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