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Oncogene-Stimulated Congestion at the KEAP1 Stress Signaling Hub Allows Bypass of NRF2 and Induction of NRF2-Target Genes that Promote Tumor Survival
John D. Hayes
,
Albena T. Dinkova-Kostova
(Lead / Corresponding author)
Research output
:
Contribution to journal
›
Article
›
peer-review
25
Citations (Scopus)
353
Downloads (Pure)
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Projects
(2)
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Dive into the research topics of 'Oncogene-Stimulated Congestion at the KEAP1 Stress Signaling Hub Allows Bypass of NRF2 and Induction of NRF2-Target Genes that Promote Tumor Survival'. Together they form a unique fingerprint.
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Keyphrases
Oncogene
100%
Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)
100%
Kelch-like ECH-associated Protein 1 (Keap1)
100%
Stress Signaling
100%
Congestion
100%
Tumor Survival
100%
Signaling Hub
100%
Cancer Cells
66%
In Cancer
33%
Overexpression
33%
Adaptor
33%
Ubiquitin Ligase
33%
Interaction Motif
33%
Cytoprotective Genes
33%
Oncoprotein
33%
IASPP
33%
Logjams
33%
Biochemistry, Genetics and Molecular Biology
Oncogene
100%
KEAP1
100%
Stress Signaling
100%
Cancer Cell
66%
Ubiquitin Ligase
33%