One remarkable molecule: filaggrin

Search results

• Finished

  Human and Mouse Genetics Studies of Filaggrin-Related Proteins in Eczema and Allergy (Joint with Trinity College Dublin)

  Barton, G. (Investigator) & McLean, I. (Investigator)

  1/10/10 → 28/02/14

  Project: Research

  • Atopic Dermatitis 100%
  • Filaggrin 43%
  • Loss of Function Mutation 36%
  • Gain-of-function mutation 34%
  • Mutation in the Filaggrin Gene 27%

• Aref#d: 22163. The Establishment of a Large Case Collection of Childhood Atopic Dermatitis: A Resource for Gemetoc Research (Joint with Trinity College Dublin)

  McLean, I. (Investigator)

  1/03/10 → 28/02/14

  Project: Research

  • Atopic Dermatitis 100%
  • Filaggrin 46%
  • Epidermis 33%
  • Gain-of-function mutation 27%
  • Loss of Function Mutation 24%

• Aref#d: 20997. Factors Modulating the Effects of Filaggrin Haploinsufficiency in Ichthyosis Vulgaris and Atopic Eczema (Intermediate Research Fellowship - Dr Sara Brown)

  Brown, S. (Investigator), Brown, S. (Investigator), Leigh, I. (Investigator) & McLean, I. (Investigator)

  1/07/09 → 30/06/15

  Project: Research

  • Filaggrin Gene 100%
  • Filaggrin 100%
  • Eczema 100%
  • Atopic Eczema 75%
  • Dermatological Research 50%