Oomycete RXLR effectors: delivery, functional redundancy and durable disease resistance

Paul R. J. Birch, Petra C. Boevink, Eleanor M. Gilroy, Ingo Hein, Leighton Pritchard, Stephen C. Whisson

    Research output: Contribution to journalReview article

    109 Citations (Scopus)

    Abstract

    To manipulate host defences, plant pathogenic oomycetes secrete and translocate RXLR effectors into plant cells. Recent reports have indicated that RXLR effectors are translocated from the extrahaustorial matrix during the biotrophic phase of infection and that they are able to suppress PAMP-triggered immunity. Oomycete genomes contain potentially hundreds of highly diverse RXLR effector genes, providing the potential for considerable functional redundancy and the consequent ability to readily shed effectors that are recognised by plant surveillance systems without compromising pathogenic fitness. Understanding how these effectors are translocated, their precise roles in virulence, and the extent to which functional redundancy exists in oomycete RXLR effector complements, are major challenges for the coming years.

    Original languageEnglish
    Pages (from-to)373-379
    Number of pages7
    JournalCurrent Opinion in Plant Biology
    Volume11
    Issue number4
    DOIs
    Publication statusPublished - Aug 2008

    Keywords

    • HOST-PLANT CELLS
    • DOWNY MILDEW
    • PHYTOPHTHORA-INFESTANS
    • PLASMODIUM-FALCIPARUM
    • FLAX RUST
    • PROTEINS
    • AVIRULENCE
    • GENE
    • ARABIDOPSIS
    • VIRULENCE

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