Optical manipulation of "drops on rails" in two dimensional microfluidic devices

C. McDougall; E. Fradet; C. N. Baroud; D. McGloin

doi:10.1117/12.893346

Optical manipulation of "drops on rails" in two dimensional microfluidic devices

C. McDougall, E. Fradet, C. N. Baroud, D. McGloin

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

When using single microfluidic droplets as isolated biological/chemical micro-reactors or arrays of droplets as 2D assaying tools, control over droplet placement is crucial to successful device implementation. Here we demonstrate a combined mechanical and optical approach to generate highly controllable arrays of droplets in pre-determined 'rails and anchors' patterns on a two-dimensional plane.

The technique combines passive mechanical forcing with selective laser action. Passive mechanical forcing provides a vehicle for droplet transport and storage and laser induced optical forcing is employed for stopping, guiding or derailing droplets as they pass through the chip. In this way intelligent operations can be performed upon arrays of droplets such as sorting, merging to initiate chemical reactions or selective removal of droplets from a predefined array. The user-generated array may then be held static against a mean flow for prolonged observation.

Original language	English
Title of host publication	Optical Trapping and Optical Micromanipulation VIII
Editors	Kishan Dholakia, Gabriel C. Spalding
Place of Publication	Bellingham
Publisher	SPIE-International Society for Optical Engineering
Number of pages	7
ISBN (Print)	9780819487070
DOIs	https://doi.org/10.1117/12.893346
Publication status	Published - 2011
Event	SPIE Optics+Photonics 2011: Optical Trapping and Optical Micromanipulation VIII - San Diego Marriott Marquis and Marina, San Diego Convention Center, San Diego, United States Duration: 21 Aug 2011 → 25 Aug 2011 http://spie.org/x57032.xml

Publication series

Name	Proceedings of SPIE
Publisher	SPIE
Volume	8097

Conference

Conference	SPIE Optics+Photonics 2011: Optical Trapping and Optical Micromanipulation VIII
Country/Territory	United States
City	San Diego
Period	21/08/11 → 25/08/11
Internet address	http://spie.org/x57032.xml

Keywords

Microfluidics
Optical manipulation
Droplet fluidics
Droplet chemistry
patterned 2D arrays

Access to Document

10.1117/12.893346

Cite this

McDougall, C., Fradet, E., Baroud, C. N., & McGloin, D. (2011). Optical manipulation of "drops on rails" in two dimensional microfluidic devices. In K. Dholakia, & G. C. Spalding (Eds.), Optical Trapping and Optical Micromanipulation VIII Article 809710 (Proceedings of SPIE; Vol. 8097). SPIE-International Society for Optical Engineering. https://doi.org/10.1117/12.893346

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title = "Optical manipulation of {"}drops on rails{"} in two dimensional microfluidic devices",

abstract = "When using single microfluidic droplets as isolated biological/chemical micro-reactors or arrays of droplets as 2D assaying tools, control over droplet placement is crucial to successful device implementation. Here we demonstrate a combined mechanical and optical approach to generate highly controllable arrays of droplets in pre-determined 'rails and anchors' patterns on a two-dimensional plane.The technique combines passive mechanical forcing with selective laser action. Passive mechanical forcing provides a vehicle for droplet transport and storage and laser induced optical forcing is employed for stopping, guiding or derailing droplets as they pass through the chip. In this way intelligent operations can be performed upon arrays of droplets such as sorting, merging to initiate chemical reactions or selective removal of droplets from a predefined array. The user-generated array may then be held static against a mean flow for prolonged observation.",

keywords = "Microfluidics, Optical manipulation, Droplet fluidics, Droplet chemistry, patterned 2D arrays",

author = "C. McDougall and E. Fradet and Baroud, {C. N.} and D. McGloin",

year = "2011",

doi = "10.1117/12.893346",

language = "English",

isbn = "9780819487070",

series = "Proceedings of SPIE",

publisher = "SPIE-International Society for Optical Engineering",

editor = "Kishan Dholakia and Spalding, {Gabriel C.}",

booktitle = "Optical Trapping and Optical Micromanipulation VIII",

note = "SPIE Optics+Photonics 2011: Optical Trapping and Optical Micromanipulation VIII ; Conference date: 21-08-2011 Through 25-08-2011",

url = "http://spie.org/x57032.xml",

}

McDougall, C, Fradet, E, Baroud, CN & McGloin, D 2011, Optical manipulation of "drops on rails" in two dimensional microfluidic devices. in K Dholakia & GC Spalding (eds), Optical Trapping and Optical Micromanipulation VIII., 809710 , Proceedings of SPIE, vol. 8097, SPIE-International Society for Optical Engineering, Bellingham, SPIE Optics+Photonics 2011: Optical Trapping and Optical Micromanipulation VIII, San Diego, United States, 21/08/11. https://doi.org/10.1117/12.893346

Optical manipulation of "drops on rails" in two dimensional microfluidic devices. / McDougall, C.; Fradet, E.; Baroud, C. N. et al.
Optical Trapping and Optical Micromanipulation VIII. ed. / Kishan Dholakia; Gabriel C. Spalding. Bellingham: SPIE-International Society for Optical Engineering, 2011. 809710 (Proceedings of SPIE; Vol. 8097).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Optical manipulation of "drops on rails" in two dimensional microfluidic devices

AU - McDougall, C.

AU - Fradet, E.

AU - Baroud, C. N.

AU - McGloin, D.

PY - 2011

Y1 - 2011

N2 - When using single microfluidic droplets as isolated biological/chemical micro-reactors or arrays of droplets as 2D assaying tools, control over droplet placement is crucial to successful device implementation. Here we demonstrate a combined mechanical and optical approach to generate highly controllable arrays of droplets in pre-determined 'rails and anchors' patterns on a two-dimensional plane.The technique combines passive mechanical forcing with selective laser action. Passive mechanical forcing provides a vehicle for droplet transport and storage and laser induced optical forcing is employed for stopping, guiding or derailing droplets as they pass through the chip. In this way intelligent operations can be performed upon arrays of droplets such as sorting, merging to initiate chemical reactions or selective removal of droplets from a predefined array. The user-generated array may then be held static against a mean flow for prolonged observation.

AB - When using single microfluidic droplets as isolated biological/chemical micro-reactors or arrays of droplets as 2D assaying tools, control over droplet placement is crucial to successful device implementation. Here we demonstrate a combined mechanical and optical approach to generate highly controllable arrays of droplets in pre-determined 'rails and anchors' patterns on a two-dimensional plane.The technique combines passive mechanical forcing with selective laser action. Passive mechanical forcing provides a vehicle for droplet transport and storage and laser induced optical forcing is employed for stopping, guiding or derailing droplets as they pass through the chip. In this way intelligent operations can be performed upon arrays of droplets such as sorting, merging to initiate chemical reactions or selective removal of droplets from a predefined array. The user-generated array may then be held static against a mean flow for prolonged observation.

KW - Microfluidics

KW - Optical manipulation

KW - Droplet fluidics

KW - Droplet chemistry

KW - patterned 2D arrays

U2 - 10.1117/12.893346

DO - 10.1117/12.893346

M3 - Conference contribution

SN - 9780819487070

T3 - Proceedings of SPIE

BT - Optical Trapping and Optical Micromanipulation VIII

A2 - Dholakia, Kishan

A2 - Spalding, Gabriel C.

PB - SPIE-International Society for Optical Engineering

CY - Bellingham

T2 - SPIE Optics+Photonics 2011: Optical Trapping and Optical Micromanipulation VIII

Y2 - 21 August 2011 through 25 August 2011

ER -

Optical manipulation of "drops on rails" in two dimensional microfluidic devices

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