Optimal frequency for vibrational optical coherence elastography (OCE) on tissue mechanical properties characterization

Duo Zhang, Jinjiang Wang, Kanheng Zhou, Ruikang Wang, Chunhui Li, Zhihong Huang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Abstract

Pathological change tends to alter tissue mechanical properties, e.g. tissue stiffness. Current elastography technology use tissue stiffness as a signature to diagnose and localize diseases. Our team focus on vibrational optical coherence elastography (OCE) for its capability to increase signal to noise ratio as well as its high resolution comparing other elastography modalities. The result highly relies on the stimulation frequency for vibrational mode might change as frequency varies. A proper frequency range is required however, there hasn't been a consensus among the research groups. In order to find the proper frequencies, several parameters measured from real experiment are input in transient model of ANSYS to simulate vibrational pattern of the sample with driving frequencies vary from 100Hz to 1000Hz. An upper limit of frequency has been discovered finally.

Original languageEnglish
Title of host publicationOptical Elastography and Tissue Biomechanics VI
EditorsGiuliano Scarcelli, Kirill V. Larin
PublisherSPIE-International Society for Optical Engineering
Number of pages6
Volume10880
ISBN (Electronic)9781510624023
DOIs
Publication statusPublished - 21 Feb 2019
EventOptical Elastography and Tissue Biomechanics VI 2019 - San Francisco, United States
Duration: 2 Feb 20193 Feb 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10880
ISSN (Print)1605-7422

Conference

ConferenceOptical Elastography and Tissue Biomechanics VI 2019
CountryUnited States
CitySan Francisco
Period2/02/193/02/19

Fingerprint

Elasticity Imaging Techniques
mechanical properties
Tissue
Mechanical properties
Stiffness
Signal-To-Noise Ratio
stiffness
Signal to noise ratio
Technology
stimulation
vibration mode
Research
signal to noise ratios
frequency ranges
signatures
Experiments
high resolution

Keywords

  • Mechanical property
  • Optical coherence elastography
  • Stimulation frequency
  • Vibration

Cite this

Zhang, D., Wang, J., Zhou, K., Wang, R., Li, C., & Huang, Z. (2019). Optimal frequency for vibrational optical coherence elastography (OCE) on tissue mechanical properties characterization. In G. Scarcelli, & K. V. Larin (Eds.), Optical Elastography and Tissue Biomechanics VI (Vol. 10880). [1088007] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10880). SPIE-International Society for Optical Engineering. https://doi.org/10.1117/12.2509411
Zhang, Duo ; Wang, Jinjiang ; Zhou, Kanheng ; Wang, Ruikang ; Li, Chunhui ; Huang, Zhihong. / Optimal frequency for vibrational optical coherence elastography (OCE) on tissue mechanical properties characterization. Optical Elastography and Tissue Biomechanics VI. editor / Giuliano Scarcelli ; Kirill V. Larin. Vol. 10880 SPIE-International Society for Optical Engineering, 2019. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
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Zhang, D, Wang, J, Zhou, K, Wang, R, Li, C & Huang, Z 2019, Optimal frequency for vibrational optical coherence elastography (OCE) on tissue mechanical properties characterization. in G Scarcelli & KV Larin (eds), Optical Elastography and Tissue Biomechanics VI. vol. 10880, 1088007, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10880, SPIE-International Society for Optical Engineering, Optical Elastography and Tissue Biomechanics VI 2019, San Francisco, United States, 2/02/19. https://doi.org/10.1117/12.2509411

Optimal frequency for vibrational optical coherence elastography (OCE) on tissue mechanical properties characterization. / Zhang, Duo; Wang, Jinjiang; Zhou, Kanheng; Wang, Ruikang; Li, Chunhui; Huang, Zhihong.

Optical Elastography and Tissue Biomechanics VI. ed. / Giuliano Scarcelli; Kirill V. Larin. Vol. 10880 SPIE-International Society for Optical Engineering, 2019. 1088007 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10880).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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AB - Pathological change tends to alter tissue mechanical properties, e.g. tissue stiffness. Current elastography technology use tissue stiffness as a signature to diagnose and localize diseases. Our team focus on vibrational optical coherence elastography (OCE) for its capability to increase signal to noise ratio as well as its high resolution comparing other elastography modalities. The result highly relies on the stimulation frequency for vibrational mode might change as frequency varies. A proper frequency range is required however, there hasn't been a consensus among the research groups. In order to find the proper frequencies, several parameters measured from real experiment are input in transient model of ANSYS to simulate vibrational pattern of the sample with driving frequencies vary from 100Hz to 1000Hz. An upper limit of frequency has been discovered finally.

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Zhang D, Wang J, Zhou K, Wang R, Li C, Huang Z. Optimal frequency for vibrational optical coherence elastography (OCE) on tissue mechanical properties characterization. In Scarcelli G, Larin KV, editors, Optical Elastography and Tissue Biomechanics VI. Vol. 10880. SPIE-International Society for Optical Engineering. 2019. 1088007. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2509411