Optimal frequency for vibrational optical coherence elastography (OCE) on tissue mechanical properties characterization

Duo Zhang, Jinjiang Wang, Kanheng Zhou, Ruikang Wang, Chunhui Li, Zhihong Huang

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    1 Citation (Scopus)
    194 Downloads (Pure)


    Pathological change tends to alter tissue mechanical properties, e.g. tissue stiffness. Current elastography technology use tissue stiffness as a signature to diagnose and localize diseases. Our team focus on vibrational optical coherence elastography (OCE) for its capability to increase signal to noise ratio as well as its high resolution comparing other elastography modalities. The result highly relies on the stimulation frequency for vibrational mode might change as frequency varies. A proper frequency range is required however, there hasn't been a consensus among the research groups. In order to find the proper frequencies, several parameters measured from real experiment are input in transient model of ANSYS to simulate vibrational pattern of the sample with driving frequencies vary from 100Hz to 1000Hz. An upper limit of frequency has been discovered finally.

    Original languageEnglish
    Title of host publicationOptical Elastography and Tissue Biomechanics VI
    EditorsKirill V. Larin, Giuliano Scarcelli
    PublisherSPIE-International Society for Optical Engineering
    Number of pages6
    ISBN (Electronic)9781510624023
    Publication statusPublished - 21 Feb 2019
    EventOptical Elastography and Tissue Biomechanics VI 2019 - San Francisco, United States
    Duration: 2 Feb 20193 Feb 2019

    Publication series

    ISSN (Print)0277-786X


    ConferenceOptical Elastography and Tissue Biomechanics VI 2019
    Country/TerritoryUnited States
    CitySan Francisco


    • Mechanical property
    • Optical coherence elastography
    • Stimulation frequency
    • Vibration

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Atomic and Molecular Physics, and Optics
    • Biomaterials
    • Radiology Nuclear Medicine and imaging


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