Optimizing peri-operative care to prevent acute kidney injury

TY - JOUR

T1 - Optimizing peri-operative care to prevent acute kidney injury

AU - Bell, Samira

AU - Lim, Michelle

PY - 2019/5

Y1 - 2019/5

N2 - Post-operative acute kidney injury (AKI) is a common complication of surgery. Rates vary according to type of surgery, ranging from 13% following gastrointestinal surgery and 10% after orthopaedic surgery to 26% following cardiac surgery [1–3]. Understanding the aetiology of post-operative AKI is vital to peri-operative optimization. However, the pathogenesis is complex and usually multifactorial (Figure 1). Renal hypoperfusion plays an important role in post-operative AKI. This can occur as a result of a number of different factors including hypovolaemia, loss of autoregulation during anaesthesia, cardiogenic shock, sepsis and high-risk medicines such as non-steroid anti-inflammatory drugs (NSAIDs) and inhibitors of the renin–angiotensin system.

AB - Post-operative acute kidney injury (AKI) is a common complication of surgery. Rates vary according to type of surgery, ranging from 13% following gastrointestinal surgery and 10% after orthopaedic surgery to 26% following cardiac surgery [1–3]. Understanding the aetiology of post-operative AKI is vital to peri-operative optimization. However, the pathogenesis is complex and usually multifactorial (Figure 1). Renal hypoperfusion plays an important role in post-operative AKI. This can occur as a result of a number of different factors including hypovolaemia, loss of autoregulation during anaesthesia, cardiogenic shock, sepsis and high-risk medicines such as non-steroid anti-inflammatory drugs (NSAIDs) and inhibitors of the renin–angiotensin system.

UR - https://www.scopus.com/pages/publications/85072327067

U2 - 10.1093/ndt/gfy269

DO - 10.1093/ndt/gfy269

M3 - Article

C2 - 30215780

SN - 0931-0509

VL - 34

SP - 757

EP - 759

JO - Nephrology Dialysis Transplantation

JF - Nephrology Dialysis Transplantation

IS - 5

ER -