Oral 5-aminolevulinic acid induced photodynamic diagnostic ureterorenoscopy - does the blood pressure require monitoring?

TY - JOUR

T1 - Oral 5-aminolevulinic acid induced photodynamic diagnostic ureterorenoscopy - does the blood pressure require monitoring?

AU - Bondad, J.

AU - Aboumarzouk, O. M.

AU - Moseley, H.

AU - Kata, S. G.

N1 - Copyright 2012 Elsevier B.V., All rights reserved.

PY - 2013/2

Y1 - 2013/2

N2 - Background: Photodynamic Diagnosis has been proven to improve detection of superficial bladder cancer and improve visualisation of resection margins. The use of 5-aminolevulinic acid as the photosensitising agent has been associated with side effects, specifically hypotension. We aimed to evaluate the effect of oral 5-ALA on the blood pressure in a group of patient who underwent Photodynamic Diagnostic Ureterorenoscopy. Methods: We carried out an observational study on all patients who underwent PDD-Ureterorenoscopy with oral 5-ALA between July 2009 and September 2011. Pre-administration, hourly post-administration and hourly post-operative blood pressures were noted. Mean arterial blood pressure and the threshold for cerebral ischaemia were calculated as well. Results: The study includes thirty-eight procedures which involved twenty-four patients with a mean age of 74 (SD ± 16.95). Hypotension was defined as

AB - Background: Photodynamic Diagnosis has been proven to improve detection of superficial bladder cancer and improve visualisation of resection margins. The use of 5-aminolevulinic acid as the photosensitising agent has been associated with side effects, specifically hypotension. We aimed to evaluate the effect of oral 5-ALA on the blood pressure in a group of patient who underwent Photodynamic Diagnostic Ureterorenoscopy. Methods: We carried out an observational study on all patients who underwent PDD-Ureterorenoscopy with oral 5-ALA between July 2009 and September 2011. Pre-administration, hourly post-administration and hourly post-operative blood pressures were noted. Mean arterial blood pressure and the threshold for cerebral ischaemia were calculated as well. Results: The study includes thirty-eight procedures which involved twenty-four patients with a mean age of 74 (SD ± 16.95). Hypotension was defined as

UR - https://www.scopus.com/pages/publications/84875384264

U2 - 10.1016/j.pdpdt.2012.06.004

DO - 10.1016/j.pdpdt.2012.06.004

M3 - Article

C2 - 23465371

SN - 1572-1000

VL - 10

SP - 39

EP - 41

JO - Photodiagnosis and photodynamic therapy

JF - Photodiagnosis and photodynamic therapy

IS - 1

ER -