Organelle Turnover: A USP30 Safety Catch Restrains the Trigger for Mitophagy and Pexophagy

Ian G. Ganley

doi:10.1016/j.cub.2018.06.067

Organelle Turnover: A USP30 Safety Catch Restrains the Trigger for Mitophagy and Pexophagy

Ian G. Ganley (Lead / Corresponding author)

MRC PPU

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

121 Downloads (Pure)

Abstract

It is crucial to remove dysfunctional mitochondria and peroxisomes to prevent cellular damage. Recent work suggests that under basal conditions USP30, a deubiquitinating enzyme, works to ensure that both of these organelles are only turned over at the right time.

Original language	English
Pages (from-to)	R842-R845
Number of pages	4
Journal	Current Biology
Volume	28
Issue number	15
Early online date	6 Aug 2018
DOIs	https://doi.org/10.1016/j.cub.2018.06.067
Publication status	Published - 6 Aug 2018

ASJC Scopus subject areas

General Biochemistry,Genetics and Molecular Biology
General Agricultural and Biological Sciences

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10.1016/j.cub.2018.06.067

Author Accepted ManuscriptAccepted author manuscript, 247 KBLicence: CC BY-NC-ND

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title = "Organelle Turnover: A USP30 Safety Catch Restrains the Trigger for Mitophagy and Pexophagy",

abstract = "It is crucial to remove dysfunctional mitochondria and peroxisomes to prevent cellular damage. Recent work suggests that under basal conditions USP30, a deubiquitinating enzyme, works to ensure that both of these organelles are only turned over at the right time.",

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Organelle Turnover: A USP30 Safety Catch Restrains the Trigger for Mitophagy and Pexophagy

Abstract

ASJC Scopus subject areas

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